ID R6Y9R2_9BACT Unreviewed; 942 AA.
AC R6Y9R2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=BN590_02354 {ECO:0000313|EMBL:CDD25386.1};
OS Alistipes sp. CAG:29.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1262694 {ECO:0000313|EMBL:CDD25386.1, ECO:0000313|Proteomes:UP000018138};
RN [1] {ECO:0000313|EMBL:CDD25386.1, ECO:0000313|Proteomes:UP000018138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:29 {ECO:0000313|Proteomes:UP000018138};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD25386.1}.
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DR EMBL; CBGS010000143; CDD25386.1; -; Genomic_DNA.
DR AlphaFoldDB; R6Y9R2; -.
DR Proteomes; UP000018138; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307:SF11; ALPHA-L-RHAMNOSIDASE; 1.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 205..374
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 383..471
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 497..831
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 833..905
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 942 AA; 106802 MW; F347F4461FD895C7 CRC64;
MASKEIKNNL KRNQILMIMK KLLLLFPLLL SCLWGIAADE FRVAELRCEY RDNPLAINTL
TPQFSWQTLS VGRGFLQAGY QIQVASDPAD LARGRKLLWD EQRKSDVSLH VRYAGRTLKP
GQRYYWRVRV SDAAGNYSPW SEIRSFAVGL LDGSDWDGAR WIAFEELPDS LRVVPGQEFN
KIKIGDRKTA LNRLPQFRRE VKVTKPVERA TVYVSGLGQF ELFLNGAKVG DNFLDPAWSD
YDRQVCYQTF DISEELQPGG NVFGVMLGNG LYNVPRERYF KALISFGYPK MIFKAEIEYA
DGTHETIVSD RAWRVTESPV TYSSIFGGED YDATRERTGW MLPGYDASAW AEPLVTTQRG
KLVSPVAEPV RVMEEFPVVS IRKTRHGKWL YDMGQNFSGT VQLEVRGKRG QSVQLNTTEL
FNFECDSITE CGGYRGEYRL TYTLRGDEVE TWRPQFTYFG QRYVLVSNAV PAGEENPEGL
PEIVTLRGLH TRNATRMAGT FHCSNNLLNK TEELIAWGIK GNMVSYFTDC PHREKLPWIE
QLHLMFGSLQ SKFDVYTLYD KMLTDMELAQ TPEGLIPDIC PEYVTFLDGF RDSPEWGSAF
VLAPWLVYEY YGDFRLVERH YEAMKRYVDY LGTKADGHIL SHGLGDWCDL GPKYPGRAQL
TSLAGTATPI YYMDAETIRK AAEKMGRKED AAKYGKLAQD IRKAYNEKYY HPQTGSYDKN
SQAGNALALY SGICEPQNRD AVLANLVQDI RSRGNALTAG DVGYNYVLRA LEQSGNSQVI
FDMNSRYDVY GYGYMLAQGA TALPESWQAL PRKSHNHLML GHLLEWFYTY VGGIRRDDSV
QAYKKFIVRP EIVGDLRSAE ASFRSPYGLI RSEWTTEQGG FDLLVEVPAN TTARIYVPAP
AGSRVCESGL EVAQCKDVES IGTEDGFRVF GVGSGIYRFS VR
//
