ID   R6YTX0_9FIRM            Unreviewed;       458 AA.
AC   R6YTX0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Propionyl-CoA carboxylase {ECO:0000313|EMBL:CDD34854.1};
GN   ORFNames=BN600_01149 {ECO:0000313|EMBL:CDD34854.1};
OS   Roseburia sp. CAG:309.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262945 {ECO:0000313|EMBL:CDD34854.1, ECO:0000313|Proteomes:UP000018292};
RN   [1] {ECO:0000313|EMBL:CDD34854.1, ECO:0000313|Proteomes:UP000018292}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:309 {ECO:0000313|Proteomes:UP000018292};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD34854.1}.
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DR   EMBL; CBGX010000114; CDD34854.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6YTX0; -.
DR   STRING; 1262945.BN600_01149; -.
DR   Proteomes; UP000018292; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   InterPro; IPR034733; AcCoA_carboxyl_beta.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR011763; COA_CT_C.
DR   InterPro; IPR011762; COA_CT_N.
DR   PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR   PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR   Pfam; PF01039; Carboxyl_trans; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 2.
DR   PROSITE; PS50989; COA_CT_CTER; 1.
DR   PROSITE; PS50980; COA_CT_NTER; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018292}.
FT   DOMAIN          1..234
FT                   /note="CoA carboxyltransferase N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50980"
FT   DOMAIN          223..458
FT                   /note="CoA carboxyltransferase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50989"
SQ   SEQUENCE   458 AA;  48750 MW;  4B75CC04CBF97C66 CRC64;
     MSNSAKMSAR QRIESLVDAN SFVEIGALVT KRNTDFNMQE KAVPADGVIT GYGVINSGLV
     YVYSQDVTAM NGSVGEMHAK KIARLYEMAM KAGAPVIGLI DCAGVRVQEA VDALAGFGEI
     YMSKVKASGV IPQISAILGS CGGGVAVSTL LSDFTFMEAE NGKLFVNSPN AIDGNRVEAC
     DTASAAFQAE AGNVDFVGEN EADVLAQIRN LIEVLPANYE DVAANEVEDD MNRVIPNFES
     LIGDPVAALT QIADANVFIE TKKDHAKDMI TGFMTLGGVT VGALANSAEQ TLSTAGCRKA
     EKFIYFCDAF GIPMITLTNV KKYASSMEEE KTIGQAVADL TCAFASAESA KVNVITGEAY
     GSAYVAMNSK HIGADLVLAL ENAKVGVMDA KSAVSVMYED DINKEADKLA ALDEKTKEFE
     EMQCKASIAA KRGYVDNIIE GSEIRKQLIY AMQMFGMR
//