ID R6ZJY3_9FIRM Unreviewed; 201 AA.
AC R6ZJY3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Thiamine-phosphate pyrophosphorylase {ECO:0000313|EMBL:CDD30762.1};
GN ORFNames=BN815_01966 {ECO:0000313|EMBL:CDD30762.1};
OS Firmicutes bacterium CAG:94.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1262989 {ECO:0000313|EMBL:CDD30762.1, ECO:0000313|Proteomes:UP000018237};
RN [1] {ECO:0000313|EMBL:CDD30762.1, ECO:0000313|Proteomes:UP000018237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:94 {ECO:0000313|Proteomes:UP000018237};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004948}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD30762.1}.
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DR EMBL; CBGU010000318; CDD30762.1; -; Genomic_DNA.
DR AlphaFoldDB; R6ZJY3; -.
DR Proteomes; UP000018237; Unassembled WGS sequence.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00564; TMP_TenI; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR036206; ThiamineP_synth_sf.
DR InterPro; IPR022998; ThiamineP_synth_TenI.
DR PANTHER; PTHR20857:SF15; THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME; 1.
DR PANTHER; PTHR20857; THIAMINE-PHOSPHATE PYROPHOSPHORYLASE; 1.
DR Pfam; PF02581; TMP-TENI; 1.
DR SUPFAM; SSF51391; Thiamin phosphate synthase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018237};
KW Thiamine biosynthesis {ECO:0000256|ARBA:ARBA00022977}.
FT DOMAIN 5..181
FT /note="Thiamine phosphate synthase/TenI"
FT /evidence="ECO:0000259|Pfam:PF02581"
SQ SEQUENCE 201 AA; 21118 MW; 098978CA1898C691 CRC64;
MFKIVCVTAR ALCPGDFLAQ LERVAAAGVD KIILREKDLP EPEYKLLAAQ ALALCRRYGV
ECAVHNFPQT ANELGAPALH LPLPRLRALS PEERAAFPVL GASCHSLEDV REAAELGCSY
GTLGHIFPTG CKPGLPPRGV ELLAQVCQAS PLPVYAIGGV GPGNIAQVKQ AGAAGACVMS
GFMTAPDPAR LVGQLRKEAE L
//
