ID   R6ZZP5_9FIRM            Unreviewed;       410 AA.
AC   R6ZZP5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Phenylacetate-CoA ligase {ECO:0000313|EMBL:CDD53993.1};
GN   ORFNames=BN633_01943 {ECO:0000313|EMBL:CDD53993.1};
OS   Ruminococcus sp. CAG:379.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262956 {ECO:0000313|EMBL:CDD53993.1, ECO:0000313|Proteomes:UP000018306};
RN   [1] {ECO:0000313|EMBL:CDD53993.1, ECO:0000313|Proteomes:UP000018306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:379 {ECO:0000313|Proteomes:UP000018306};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD53993.1}.
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DR   EMBL; CBHF010000230; CDD53993.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6ZZP5; -.
DR   Proteomes; UP000018306; Unassembled WGS sequence.
DR   GO; GO:0047475; F:phenylacetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0010124; P:phenylacetate catabolic process; IEA:InterPro.
DR   CDD; cd05913; PaaK; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR028154; AMP-dep_Lig_C.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR011880; PA_CoA_ligase.
DR   PANTHER; PTHR43845; BLR5969 PROTEIN; 1.
DR   PANTHER; PTHR43845:SF1; BLR5969 PROTEIN; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF14535; AMP-binding_C_2; 1.
DR   PIRSF; PIRSF006444; PaaK; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:CDD53993.1}.
FT   DOMAIN          63..270
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          319..409
FT                   /note="AMP-dependent ligase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14535"
SQ   SEQUENCE   410 AA;  46040 MW;  2606FCE84AB48303 CRC64;
     MKMTETQFNL IKAQLKKLTS QPCFYQRKLE GIHVDQIQSQ EDFETLPFTW KGDLREAYPL
     GLQAVPDEEI IRIHSSSGTT GTPVIIPYTR QDVEDWTEMF KRCYETAGIT NLDRIQITPG
     YGLWTAGIGF QNGAERLGAM VIPMGPGNTD KQLRMMMDMK STVLCATSSY ALLLAEEIAK
     RGIGNRIHLR KGVIGSERWG EKMRNRIANE LGVQLYDIYG LTEVYGPGIG ISCDHACGIH
     VWTDYLYFEV VDPKTGKNVP DGEIGELVIT TLHKQGAPLI RYRTHDLTRV IPGECPCGCP
     FPRIDTILGR TDDMVKVKGV NIFPSQIEEL LTGIEGASSE YQFMLDHMNG KDICTLFVEA
     NDGANRYELE IELQNAFKSK IGISVNVKPV SIGELPRSEK KSTRVFDNRY
//