ID R7A106_9BACE Unreviewed; 1383 AA.
AC R7A106;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BN800_01668 {ECO:0000313|EMBL:CDD49274.1};
OS Bacteroides sp. CAG:875.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1262752 {ECO:0000313|EMBL:CDD49274.1, ECO:0000313|Proteomes:UP000018287};
RN [1] {ECO:0000313|EMBL:CDD49274.1, ECO:0000313|Proteomes:UP000018287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:875 {ECO:0000313|Proteomes:UP000018287};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD49274.1}.
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DR EMBL; CBHD010000083; CDD49274.1; -; Genomic_DNA.
DR Proteomes; UP000018287; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 2.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF69322; Tricorn protease domain 2; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1383
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004439297"
FT DOMAIN 844..1064
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1116..1231
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1268..1367
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT REGION 1363..1383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1365..1383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1164
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1383 AA; 156665 MW; 1497B3EBCD5D7533 CRC64;
MKNYTLILLF LLGLALPSRA QRLLEKDFQV LNMNDGIADN DIHSIEKDAE GFIWFGTSSG
LSRYDGQDFK TFRITEALHR TVGKVVSLNK DYLLVRSERT LFLFDKQRER FLSLWDAERN
RIVDFTRFVA TSDGHCWGVA GNTLSEMDLS TASFREDTAF VHLQSTVKVE SESELMMLCL
GEDGKSLYGI GRKGTVYRYD RGQKRLETLC VRPMQRDVLV TSALQGDNFL WITTLGDGLY
GYDLTTCAVH HWNYDPANRN EQLSHNDVFQ LLPLGDSRYM ALTWNGYTML TLTPERELKM
HAFHSFGNSG NQYIETRMVT GYYDPEGLLW IGTEGGGVLF SDLRQLFYQQ YAQAHSNELC
GIQMDKEGYL WLATFHKGLL RSTQPFDGIQ PLDFQPMAPG VVAIHTVLCS AADTCGGLWF
GSRNGRVLRY GEDGSWQALG LGKETSPEVW SLLPLSENEA WAGTSNGLYR VNLRKGTSVK
VEWNNPQIPD HIQVRALALS DARTLWLGTT RGLLRLSMEG NRVVRSCAGY EREADLSPTD
VEVRALLFGS DHVLWVGYAG NGLGACSPVD NRILFHYTTE DGLCSNFVTA LAEDGDHSLW
VGSNSGISRL SRHLQSFYNF YISGSNRSVF FGKDFLFWGN HSTLTYFRPS RLRFHYPIEK
GRVVFTDLEV NHTSVQIGEH VNGQVILSRS LLYTKGIHLN HANRNFSLSF SNLLYLHKLQ
KYLYRLYPYQ EEWIMADEGD KISYDRLPAG EYTFQVKTVF QDQSEGEVSS LDIVVDPHWS
ETWWFRLLAT LGLMGILLVY IHRVRLKEKR VQYELRLEHE LFTVNMERNK EIELRKERED
FFTMAAHELR TPLTLILAPL RELLHKTPTS HPFYAKLSMM FKYAEGLHTL TDRLLYIQKA
EAGMVKLRLS QVDVEALLVD VAQGFQSLAA ERKIDYAWEL APDCVPVWAD REKLSSVVQN
LISNAFKYTP EGGKIRLKVE RKEIDGKHFC CLSVSDTGKG IDSVLLQHIF DPFVTGKEAP
AVSTHVGIGL KIVKHIVEMH HGRVTVDSEP GKGSLFCVYL PEGKSHFNED DCTWEESSEA
VVAPEVSSVV PEMIFPATSE HVAEAKEEKL SAARQTVLVI EDNTDMRRYL CELLRKQYRV
LEAENGEEGL KTAVEQVPDL VLSDVMMPVM DGFTCCAELR KRKETAHIPV LMLTAKAEDR
DSVEASRRGA DDYLRKPFNP EVLLAKIACL LDMRRRLKQI YTRTLLHASS AASASTEKPE
SVESEFMQKV WACIEANVSN PDFNVKVLSG ELHMSLATLY RKLKQHTDLS AVELIRHIRM
TKAALLLMET SLSVTEVAER VGFNDLPTFR KHFTDMFGVS PSKYAESGQG GNNKSQPEAG
TGV
//
