ID R7A7G3_9BACE Unreviewed; 834 AA.
AC R7A7G3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:CDD51434.1};
GN ORFNames=BN800_02556 {ECO:0000313|EMBL:CDD51434.1};
OS Bacteroides sp. CAG:875.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1262752 {ECO:0000313|EMBL:CDD51434.1, ECO:0000313|Proteomes:UP000018287};
RN [1] {ECO:0000313|EMBL:CDD51434.1, ECO:0000313|Proteomes:UP000018287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:875 {ECO:0000313|Proteomes:UP000018287};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD51434.1}.
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DR EMBL; CBHD010000177; CDD51434.1; -; Genomic_DNA.
DR AlphaFoldDB; R7A7G3; -.
DR Proteomes; UP000018287; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR040605; Glyco_hydro2_dom5.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF18565; Glyco_hydro2_C5; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..834
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004427462"
FT DOMAIN 34..181
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 191..295
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 303..545
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 656..714
FT /note="DUF4982"
FT /evidence="ECO:0000259|Pfam:PF16355"
FT DOMAIN 728..830
FT /note="Glycoside hydrolase family 2"
FT /evidence="ECO:0000259|Pfam:PF18565"
SQ SEQUENCE 834 AA; 94479 MW; B79FC8F9D3E35E4C CRC64;
MKKLLLFLHV FCCSCFMVFS TTVSTCRERI NLGDCWRFHN GDEPEAVDAN FEDTGWQLLD
LPHDWAIEGN FSKDNPSGTG GGALPGGIGW YRKTFVPEKA DSDMKFRIVF DGVYMNSEVY
LNGILLGRRP YGYITFSYDL TPHLKWGEKN VLAVRVDNSE QPNSRWYSGC GIYRNVWLVK
TEAVHVGEWG TYVTAPVVNK SKAIVRVQTT VSNETDVDAK VTVCSSLFDA EGKCVAKTDT
LCQVGGQADA VAVQQLSVAD PHRWDIESPY LYTLVTELMD GEHCIDRYET ITGIRSFKFD
AQKGFVLNGK PTKINGVCMH HDLGCLGAAV NMRAIERQLE ILKEMGCNGI RCSHNPPAPE
LLDLCDQMGF IVMDEAFDMW RKKKTAHDYA RYFNDWHERD LHDFIMRDRN HPSIFMWSIG
NEVLEQWSHA NADTLSLEEA NLILNFGHSK NMLAKEEEMS VNSLLTKKLA DIVRELDPTR
PVTAGCNEPN PFNHLFKSGA LDIIGYNYHN INILDVPKNF PSKPFIITES NSTLATRGYY
KMPSDKEFIW PERWDKPFYD PSFSCSSYDN CHAPWGNTHE ETLKLIRDND FISGQYVWTG
FDYIGEPTPF GWPARSSYFG IVDLAGFPKD TYYLYQSEWS EEQVLHLFPH WNWKPGQVVD
MWCYYNKADE VELFVNGKSQ GVKSKTPDCL HAMWRVEYEP GSVKVIARKN GKVVGEKEIR
TAGEPVQIRL TPDRSQLTAN GKDLSFITVE ILDKDGNLCP NADNLVNFKV EGDIFIAGVD
NGSPISMEHF KANKRRAFYG KCLVVIQNQG KQGTAHLVAT SNGLQSANVK ITID
//
