ID R7AJM1_9ACTN Unreviewed; 616 AA.
AC R7AJM1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Histidine kinase domain-containing protein {ECO:0000259|PROSITE:PS50109};
GN ORFNames=BN592_00414 {ECO:0000313|EMBL:CDD58555.1};
OS Eggerthella sp. CAG:298.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Eggerthella.
OX NCBI_TaxID=1262876 {ECO:0000313|EMBL:CDD58555.1, ECO:0000313|Proteomes:UP000018266};
RN [1] {ECO:0000313|EMBL:CDD58555.1, ECO:0000313|Proteomes:UP000018266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:298 {ECO:0000313|Proteomes:UP000018266};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD58555.1}.
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DR EMBL; CBHI010000021; CDD58555.1; -; Genomic_DNA.
DR AlphaFoldDB; R7AJM1; -.
DR STRING; 1262876.BN592_00414; -.
DR Proteomes; UP000018266; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00497; SBP_bac_3; 2.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00062; PBPb; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018266};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 526..616
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 616 AA; 67999 MW; 14113B80AD3CE0A2 CRC64;
MRSTDAQKRD ATRVISVRRV MFAALVICAL IFGGTLLGAI PGVSGALSTS GDSEASATST
ASGNSEIFAE KAFAEPAQSS SEDNSKEVRI GYYYGDTAFQ DGFGDDERKS GYAYEYYQRL
APYAGWDYTY RYLTRSEAIE ALRNGEVDIV AGINKTPQLE KEFLFSSADM GLDGNPLYFA
VNKNRGDLLA ELDQAQEDLL TNDPNFLADN RKKYYANSGM TTALTKEEHA WLEEKGSITL
GYLSGNLPIS GHDDQGKPTG VLGSALPIME EYLGIPIKTK AFDSRYAMRE AIKNNEVDVI
FPVYDDAWSR EKEDLYQTTP LVEDRIMVAY TGDYDDDVLK RVASTEAAIG QQEFLEQYDP
SAELVNYPSR DEAFRAMSRG EVDSVIGNAS IMQLFIAEHP EYDSFNTAYL EASEGFSFAV
SRDDPTLAVI MQEATQQIDD TLITNAMIRY SEARAPFSLV EVIRHYALPL LVIGLVIIAA
IVIVFLRYRR QVNLFNKHQA AAREALQTAL DAADNASAAK TSFLSNMSHD IRTPLNAIIG
MTAIAGANIN DTNRVKDCLA KISSSGKHLL SLINEILDVS KIESGRIELS EEPFDLSVML
KDLVDINRPQ ADAKRQ
//
