ID   R7B0I0_9FIRM            Unreviewed;       301 AA.
AC   R7B0I0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Cell division protein FtsX {ECO:0000256|ARBA:ARBA00021907, ECO:0000256|PIRNR:PIRNR003097};
GN   ORFNames=BN633_01644 {ECO:0000313|EMBL:CDD53657.1};
OS   Ruminococcus sp. CAG:379.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262956 {ECO:0000313|EMBL:CDD53657.1, ECO:0000313|Proteomes:UP000018306};
RN   [1] {ECO:0000313|EMBL:CDD53657.1, ECO:0000313|Proteomes:UP000018306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:379 {ECO:0000313|Proteomes:UP000018306};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter FtsEX involved in asymmetric
CC       cellular division facilitating the initiation of sporulation.
CC       {ECO:0000256|PIRNR:PIRNR003097}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR003097}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family. FtsX
CC       subfamily. {ECO:0000256|ARBA:ARBA00007379,
CC       ECO:0000256|PIRNR:PIRNR003097}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD53657.1}.
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DR   EMBL; CBHF010000163; CDD53657.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7B0I0; -.
DR   Proteomes; UP000018306; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.3040; -; 1.
DR   InterPro; IPR003838; ABC3_permease_dom.
DR   InterPro; IPR004513; FtsX.
DR   InterPro; IPR040690; FtsX_ECD.
DR   NCBIfam; NF038347; FtsX_Gpos; 1.
DR   PANTHER; PTHR47755; CELL DIVISION PROTEIN FTSX; 1.
DR   PANTHER; PTHR47755:SF1; CELL DIVISION PROTEIN FTSX; 1.
DR   Pfam; PF02687; FtsX; 1.
DR   Pfam; PF18075; FtsX_ECD; 1.
DR   PIRSF; PIRSF003097; FtsX; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR003097};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618,
KW   ECO:0000256|PIRNR:PIRNR003097};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR003097};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR003097};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        271..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          60..152
FT                   /note="FtsX extracellular"
FT                   /evidence="ECO:0000259|Pfam:PF18075"
FT   DOMAIN          175..298
FT                   /note="ABC3 transporter permease protein"
FT                   /evidence="ECO:0000259|Pfam:PF02687"
SQ   SEQUENCE   301 AA;  33079 MW;  28B57E5A2DD6F33E CRC64;
     MKLSGVRYLI KQGVDNVWKN RVMAFASFCV LLVSLLLVGI SCLFFLNLNS IIGGIEDKNE
     VIIYIKDNTS DQQIQEMGKK LEQMDNVSSV SFYSKEDAYA DLKSDMMEYE VLFESLGDDN
     PLPDAYRIRV TDISRLSDTL SSLNSMQDVD RIRAPYDFVN VLTGLRRIVS VVALAVVVAL
     VIVSMVIISN TTRASVFARR REISIMKYVG ATNAFIRLPF FVEGMLTGLM AGAVATVITW
     FSYDSLVDLL KADADILSII GVGSIITYND VALPVTLAYL GAGALVGAIG SVISTRKHLK
     V
//