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Database: UniProt
Entry: R7C820_9CLOT
LinkDB: R7C820_9CLOT
Original site: R7C820_9CLOT 
ID   R7C820_9CLOT            Unreviewed;       676 AA.
AC   R7C820;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   10-APR-2019, entry version 21.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN737_00509 {ECO:0000313|EMBL:CDD74226.1};
OS   Clostridium sp. CAG:62.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium; environmental samples.
OX   NCBI_TaxID=1262828 {ECO:0000313|EMBL:CDD74226.1, ECO:0000313|Proteomes:UP000018137};
RN   [1] {ECO:0000313|EMBL:CDD74226.1, ECO:0000313|Proteomes:UP000018137}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:62 {ECO:0000313|Proteomes:UP000018137};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDD74226.1}.
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DR   EMBL; CBHQ010000080; CDD74226.1; -; Genomic_DNA.
DR   Proteomes; UP000018137; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000018137};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018137};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    290    311       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    317    338       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    350    374       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    394    418       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    460    483       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    524    544       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    556    580       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    587    610       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    622    641       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    653    673       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        4    166       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   676 AA;  74825 MW;  3890B9D01E57CCFA CRC64;
     MSQNLVVGFI GNPNCGKTTL FNAFTGANLK VANWPGVTVE KVEGALKYHN NTYRLVDLPG
     TYSLTSYTME EQVSRQYILS DDVDVIVDVA DASSLERNLY LTLQLLELGK PVVLALNMMD
     IVEKRGMEID LHRLPEMLGI PVIPVSARKR TGLEILMHAV SHHKDAVMPD KLVHHHTMPS
     HHKHDHHADH AMVYSDEIED KIDSISDALQ KRYPEIIHVR WCAIKLLEGD KEISEKYPVD
     LPQVLDRSYE SEIINQKYEF IEEIVQEVLV NKEEKAQSTD KADRILTHPI FGIPIFLGIM
     ALVFLLTFTV GDFISGYFEL AVEWLSGFIS NALAAWQVNP AVTSLLVDGI IAGVGGILTF
     LPNIFILFLA LAFLEDSGYM ARVAYVMDGI MGRIGLSGRA FIPMILGFGC SVPAVMASRA
     LEDNKDRMKT MLVTPFMSCS ARLPIYILFS QMFFGKHAMI AAYSMYVIGL VVAVFVAFIL
     HIVDKKEANG MLIIELPEYK APSARTIWIY VWEKVKDYLT KAGTVIFLAS IAMWLLLNFG
     IHGYTNEMSE SFGAAIGHFI VPVLKPIGLG YWQIAVALIA GISAKEVVVS SCAVLFGIAN
     VNSAAGMGAL HQALGAAGFG MVNAYCLMIF CLLYIPCFAT LATIRKESGS TKFMFLAAGF
     QLVMAWLASF VVFQVF
//
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