ID   R7CVI1_9BACE            Unreviewed;       297 AA.
AC   R7CVI1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=AdoMet activation domain-containing protein {ECO:0000259|PROSITE:PS50974};
GN   ORFNames=BN666_01312 {ECO:0000313|EMBL:CDD81881.1};
OS   Bacteroides sp. CAG:462.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262740 {ECO:0000313|EMBL:CDD81881.1, ECO:0000313|Proteomes:UP000018063};
RN   [1] {ECO:0000313|EMBL:CDD81881.1, ECO:0000313|Proteomes:UP000018063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:462 {ECO:0000313|Proteomes:UP000018063};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD81881.1}.
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DR   EMBL; CBHU010000034; CDD81881.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7CVI1; -.
DR   STRING; 1262740.BN666_01312; -.
DR   Proteomes; UP000018063; Unassembled WGS sequence.
DR   GO; GO:0008705; F:methionine synthase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.288.10; Cobalamin-dependent Methionine Synthase, domain 2; 1.
DR   Gene3D; 3.10.196.10; Vitamin B12-dependent methionine synthase, activation domain; 1.
DR   InterPro; IPR004223; VitB12-dep_Met_synth_activ_dom.
DR   InterPro; IPR037010; VitB12-dep_Met_synth_activ_sf.
DR   PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR   Pfam; PF02965; Met_synt_B12; 1.
DR   SUPFAM; SSF56507; Methionine synthase activation domain-like; 1.
DR   PROSITE; PS50974; ADOMET_ACTIVATION; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00346};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018063};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU00346}.
FT   DOMAIN          1..297
FT                   /note="AdoMet activation"
FT                   /evidence="ECO:0000259|PROSITE:PS50974"
SQ   SEQUENCE   297 AA;  34247 MW;  748728FF3914CCFE CRC64;
     MTITYRIHEQ TDYINWIYFF HAWGFQPRFA EIGNVHGCDA CRAMWLTDFP VEDRPKAAEA
     MQLFKEAQRM LWQLDEDYKV HGVFRLCKAN SKGDNLILDD ETVFPLLRQQ TVKKPGDPCL
     CLSDFVRPME QGVADTVGLF ATTVDREMEE LYENDPYKRM LVHVLAERLA EAAAERLHEQ
     VRKEFWGYAK DERLTIPQLL KEEYQGIRPA VGYPSLPDQS VTFLLDALLD MKQIGIHLTE
     NGMMDPRASV CGLMFAHPQS HYFAVGKIGE DQLADYASRR GKSLEEMRKF LAANLSE
//