ID R7F9G7_9FIRM Unreviewed; 716 AA.
AC R7F9G7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Dockerin type I repeat protein {ECO:0000313|EMBL:CDE11959.1};
GN ORFNames=BN611_01238 {ECO:0000313|EMBL:CDE11959.1};
OS Ruminococcus sp. CAG:330.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262954 {ECO:0000313|EMBL:CDE11959.1, ECO:0000313|Proteomes:UP000018377};
RN [1] {ECO:0000313|EMBL:CDE11959.1, ECO:0000313|Proteomes:UP000018377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:330 {ECO:0000313|Proteomes:UP000018377};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 26 family.
CC {ECO:0000256|ARBA:ARBA00007754, ECO:0000256|PROSITE-ProRule:PRU01100}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE11959.1}.
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DR EMBL; CBIH010000041; CDE11959.1; -; Genomic_DNA.
DR AlphaFoldDB; R7F9G7; -.
DR STRING; 1262954.BN611_01238; -.
DR Proteomes; UP000018377; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016985; F:mannan endo-1,4-beta-mannosidase activity; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:InterPro.
DR GO; GO:0006080; P:substituted mannan metabolic process; IEA:InterPro.
DR CDD; cd14256; Dockerin_I; 1.
DR Gene3D; 1.10.1330.10; Dockerin domain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR002105; Dockerin_1_rpt.
DR InterPro; IPR016134; Dockerin_dom.
DR InterPro; IPR036439; Dockerin_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR022790; GH26_dom.
DR InterPro; IPR000805; Glyco_hydro_26.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR40079:SF4; GH26 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR40079; MANNAN ENDO-1,4-BETA-MANNOSIDASE E-RELATED; 1.
DR Pfam; PF00404; Dockerin_1; 1.
DR Pfam; PF02156; Glyco_hydro_26; 1.
DR PRINTS; PR00739; GLHYDRLASE26.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF63446; Type I dockerin domain; 1.
DR PROSITE; PS51766; DOCKERIN; 1.
DR PROSITE; PS51764; GH26; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PROSITE-
KW ProRule:PRU01100};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01100}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018377};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 216..549
FT /note="GH26"
FT /evidence="ECO:0000259|PROSITE:PS51764"
FT DOMAIN 648..716
FT /note="Dockerin"
FT /evidence="ECO:0000259|PROSITE:PS51766"
FT REGION 555..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 381
FT /note="Proton donor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01100"
FT ACT_SITE 497
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01100"
SQ SEQUENCE 716 AA; 79728 MW; 9D3B150DB6F45D00 CRC64;
MYNDTCEICS EQPNIIFDME KGKEDNMRKF WKRAGSVGIA AALLAGILQV APTSFVSMAA
DEPLFSSECE DLTLSSDATV ATKVYNDEYP GYTGEGFVWV TSAGTMSFTI DAPETGMYRL
MTRCLVYLGN VGETRQATVS VTRSDDSTWS KDVKIAHTES WNDYSWGDIK LTKGENTITF
GGGWGYCLYD NMTLSKTPKP EYDKATDVLT DAKATSQTQA LMTYLKSVYG SHIISGQQEI
YGGGHDNNME LEFDYIKNTT GKLPAIRGFD FMNYNPLYGW EDGTTERAIE WAKDRNGIVT
ASWHINVPID FDKYELGDEV DWQKCTYKNY QVSNSTFNTA NAVKEGTKEY EYFQECMKDL
AEQLTKLQDA GVPIILRPLH EAQGNEGNYG DGTAWFWWGD RGAEVYKELW KLLYNTLTEK
YNLHNIIWEY NSYNYANSDT WYPGDDYVDI VAYDKYNCEY NRDDGLSFGT PNLSAISSVF
NYLYELTDGK KMVAMAENDS IPSVENMTIE NAGWLYFCPW YGDHLMSSTY NDPDELKVTY
NSDYCITLDE LPKNLYGSAT PGTTTETKET TTAEETTTTE ATETTDDTTV TSAETTTAST
DESTKTTETT VTTSDSTKST EETTVSSDTT TSSEKTTTVS TDESTEPSAD LYGDVNLDGD
VDLSDAVLMN KAIAGQVSLN AAAKANADCQ KDGIVSSDDS MTLLKFLVHL VNSLPQ
//
