ID R7FLE4_9CLOT Unreviewed; 449 AA.
AC R7FLE4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:CDE14557.1};
GN ORFNames=BN670_00861 {ECO:0000313|EMBL:CDE14557.1};
OS Clostridium sp. CAG:470.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262812 {ECO:0000313|EMBL:CDE14557.1, ECO:0000313|Proteomes:UP000018084};
RN [1] {ECO:0000313|EMBL:CDE14557.1, ECO:0000313|Proteomes:UP000018084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:470 {ECO:0000313|Proteomes:UP000018084};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE14557.1}.
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DR EMBL; CBII010000047; CDE14557.1; -; Genomic_DNA.
DR AlphaFoldDB; R7FLE4; -.
DR Proteomes; UP000018084; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032834; NatK_C.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CDE14557.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CDE14557.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 343..447
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
SQ SEQUENCE 449 AA; 52174 MW; D7ECFE3A9599F3FB CRC64;
MNVLNNIWLA LSTPNETLIS VFSIPFIFLI EMPLSFYLIC NLLNIQYTKK VKYIYIISTA
IIAVFANYCI SWPYNILFNY ATAFIVLYFV MKLGFTKSTI ATLFPSIVFN LVGSLLANPY
LDLLHITYEQ NNTIFIYRVP FNLLMYLVVF ILILIFKYRK VTLNILEDFD KKTKSIITIN
FVFGFITIFL QGILSSKYID ILPIEFTFFN FIFLLAYFGL SFYSLAKIMN LVTTTKKLES
AEEYNKTLHI LHDSVRGFKH DFDNIVTTIG GYIKTNDMDG LKSYYSQLEE DCTKVNNLYV
LDPDIINNPG VYNLITAKYN EALEKGIKVN LTVLLDLNDL HMKIYEFARI LGILLDNAIE
AASECDEKIL NIVFRNESKN NRNIILIENT YKDKDVDIEQ IFNKGVSGKQ NHTGLGLWEI
RQILKKNNNV NLYTNKNEKY FSQQLEIYY
//
