ID   R7GYB9_9FIRM            Unreviewed;       702 AA.
AC   R7GYB9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Endoglucanase {ECO:0000313|EMBL:CDE32105.1};
GN   ORFNames=BN645_01588 {ECO:0000313|EMBL:CDE32105.1};
OS   Ruminococcus sp. CAG:403.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262958 {ECO:0000313|EMBL:CDE32105.1, ECO:0000313|Proteomes:UP000017925};
RN   [1] {ECO:0000313|EMBL:CDE32105.1, ECO:0000313|Proteomes:UP000017925}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:403 {ECO:0000313|Proteomes:UP000017925};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE32105.1}.
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DR   EMBL; CBIS010000118; CDE32105.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7GYB9; -.
DR   STRING; 1262958.BN645_01588; -.
DR   Proteomes; UP000017925; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR040753; DUF5620.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR018087; Glyco_hydro_5_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR31297:SF41; ENDOGLUCANASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01830)-RELATED; 1.
DR   PANTHER; PTHR31297; GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   Pfam; PF18522; DUF5620; 2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE   4: Predicted;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023326};
KW   Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017925};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..702
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038506892"
FT   DOMAIN          87..200
FT                   /note="DUF5620"
FT                   /evidence="ECO:0000259|Pfam:PF18522"
FT   DOMAIN          226..336
FT                   /note="DUF5620"
FT                   /evidence="ECO:0000259|Pfam:PF18522"
FT   DOMAIN          393..674
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
FT   REGION          25..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..68
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   702 AA;  76493 MW;  42F537B6E4AD6E10 CRC64;
     MMNWKKGLAV VLAGLSLAIP LSGCKKDTAD SSSEASTSAA ESSGTDAPEA TTTKEETTVT
     EHVSPTETVS STLGIEKNGI NMTLDRDKTN TYKANLDQFI QDGDQVQSFT FIFYAADGSS
     NIGTYKGACG VSVKDGSSAA TDKNWYQSDD FSQEANGSYI ELNWTVPAEV QKDIDPSGQV
     LVGYWWGDVQ QVRLDSIVCT FTRTATVPVD GTKSISPNTT LDYADESAKE AKISLGDLIT
     EGDTLQTVTF DVSGGGSLGK FTGAFGVSVA EDSKAATDKG WYQSSNVVLF TDSNAVSLTW
     IVPDEVKADI QAGGEVMLGY WWSDQNPVTL TNVSVRYSND GITGSTATTA TPADSEKKEA
     VDNTVEAGDM TASEIVDNIR IGWNLGNTFD SYNTSSSDTE TGWGNPKTTK AMIDTVKDAG
     FNAIRIPVTW GEHLSADYTI DANWMARIKE VVDYAYDQNM FVILNVHHDD ALWLVPTNAK
     LEEDKTILSK IWTQIGTTFQ DYDSHLIFEG MNEPRVIGSS TEWSGGTPEE RQVINQLFVT
     FTDTVRGLGG NNAKRALIVT SHAQSIVKDA VQAIEIPNND PNIIVSIHSY APWDFAGTDS
     ERSTWGTDAD KQELDQNFQF LKETFVDKGI PVILDEFGAV NKNNEADRDA YYEYYVKSAK
     AHGGIKCFVW DNGTQKEFGL LNRSQNSWYF PSIVDAMMRG AA
//