ID R7HP40_9BACT Unreviewed; 623 AA.
AC R7HP40;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Putative pyruvate carboxylase subunit B {ECO:0000313|EMBL:CDE40698.1};
GN ORFNames=BN585_01636 {ECO:0000313|EMBL:CDE40698.1};
OS Prevotella sp. CAG:279.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262924 {ECO:0000313|EMBL:CDE40698.1, ECO:0000313|Proteomes:UP000018375};
RN [1] {ECO:0000313|EMBL:CDE40698.1, ECO:0000313|Proteomes:UP000018375}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:279 {ECO:0000313|Proteomes:UP000018375};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE40698.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBIX010000054; CDE40698.1; -; Genomic_DNA.
DR AlphaFoldDB; R7HP40; -.
DR Proteomes; UP000018375; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Pyruvate {ECO:0000313|EMBL:CDE40698.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018375}.
FT DOMAIN 5..292
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT DOMAIN 546..622
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 623 AA; 67992 MW; 0F56F517BBE289D2 CRC64;
MSRSLKVRDL TLRDGQQSLF ATRMKQESID KLLPLYKDAG FYAMEVWGGA VPDSVMRYLG
EDPWVRLKTI SDAMGGVSKL TALSRGRNLF GYVPYPTSVL EGFYKEAIKN GLNIMRIFDA
LNDLDNVKES IKLINEMGGI ADGAVCYTVD PKTEAPAEKK GFFAKLFGSK KVEEPEKIFT
DEYFVEKAKG MEAYGAKIIT LKDMAGLVNP LRAASLISKI KAAVNVPVDF HTHCTPGYGL
ASVVMAMLHG VDIVDTNIWY FGGGSAAPAI ELVYLFAKRL GIELEVNMEA VGRIREQLKG
VRTALADFDL HKGDFPHDFD PLKDTLPANI EALFDKAVEA AKANDEDALL DACHAIEDYF
NFPKPNLLVK NAEVPGGMYS NMVAQLKALN ASDVLDDAMK LIPKVRRDAG LVPLVTPTSQ
IVGSQAVSLA IDRKKGNADY TTKSNQFISL IKGEYGKTPV AITPEFREQI TGSAVERPYD
VASYKAPENP VLKELGGCKL AENEQEYLLL QLLPTVANGF LKKRREADHK ASAPAVEEKA
EAAAVADDAP ITGPVERAPM GGKVVEVKVK AGDKVKKGDL LLVYEAMKME NELTAEKDAV
VKRVFVTVDD VVGTDAPLIE FEA
//
