ID R7HUL6_9CLOT Unreviewed; 507 AA.
AC R7HUL6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=UMUC domain protein DNA-repair protein {ECO:0000313|EMBL:CDE42663.1};
GN ORFNames=BN648_00039 {ECO:0000313|EMBL:CDE42663.1};
OS Clostridium sp. CAG:411.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262802 {ECO:0000313|EMBL:CDE42663.1, ECO:0000313|Proteomes:UP000018022};
RN [1] {ECO:0000313|EMBL:CDE42663.1, ECO:0000313|Proteomes:UP000018022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:411 {ECO:0000313|Proteomes:UP000018022};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE42663.1}.
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DR EMBL; CBIY010000035; CDE42663.1; -; Genomic_DNA.
DR AlphaFoldDB; R7HUL6; -.
DR STRING; 1262802.BN648_00039; -.
DR Proteomes; UP000018022; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProt.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF35; DNA REPAIR PROTEIN HOMOLOG YOBH; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000018022}.
FT DOMAIN 8..236
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT COILED 416..469
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 507 AA; 58174 MW; 00087A834F424EDE CRC64;
MAGQERTYIA IDLKSFYASV ECIERNLDPL RTNLVVADLS RTEKTICLAV SPSLKKYGIS
GRARLFEVVQ KVKEVNCERM QQAAGRRFLG KSYDDKALKA CSELALDYIV APPRMAHYIQ
YSTRIYDIYL NYIAPEDIHV YSIDEVFMDV TEYLSTYKLT AYELAEKMIQ DVLQQTGITA
TAGIGTNLYL SKVAMDIVAK HITPNKNGVR IAQLDEENYR RYLWTHQPIT DFWRVGRGYA
KRLAEKGIYT MGDVARCSIG KPKDFYNEEL LYKIFGINAE LLIDHAWGWE PCTLADVKAY
KPDSNSISMG QVLQCPYDFS KARLVVKEMV DLLALDLLDK KVITKQLVLT IGYDKENLTD
KKKTYKGELS TDYYGRKIPK HAHGTVNIKQ YTSSTHLLTE AVIGLYDEIV NPSLWIRRIN
IVANNLREEN TLQEEESYEQ MDLFTDYAAL EQKRKTEEAE RKRERKMQQT MLEVKKKFGK
NAIIKGMNLE EGATTIQRNK QIGGHKA
//
