ID   R7J062_9BACT            Unreviewed;       618 AA.
AC   R7J062;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:CDE57013.1};
GN   ORFNames=BN799_01110 {ECO:0000313|EMBL:CDE57013.1};
OS   Prevotella sp. CAG:873.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1262936 {ECO:0000313|EMBL:CDE57013.1, ECO:0000313|Proteomes:UP000018078};
RN   [1] {ECO:0000313|EMBL:CDE57013.1, ECO:0000313|Proteomes:UP000018078}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:873 {ECO:0000313|Proteomes:UP000018078};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cyclic nucleotide phosphodiesterase class-
CC       III family. {ECO:0000256|ARBA:ARBA00025742}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE57013.1}.
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DR   EMBL; CBJF010000063; CDE57013.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7J062; -.
DR   Proteomes; UP000018078; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 3.60.21.40; GpdQ, catalytic alpha/beta sandwich domain; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR042283; GpdQ_catalytic.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR42988:SF2; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CBUA0032-RELATED; 1.
DR   PANTHER; PTHR42988; PHOSPHOHYDROLASE; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   Pfam; PF13360; PQQ_2; 1.
DR   SMART; SM00564; PQQ; 5.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018078}.
FT   DOMAIN          23..199
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
SQ   SEQUENCE   618 AA;  68956 MW;  8FB659B8C8CDA29A CRC64;
     MHLNRFLVTF LVAIAIPMAW SQRLAVLSDI HVTPGNANDV QLRRVVDEIN AGNYDAVIID
     GDLTNEGSDE QLANVKSIVS AIRFPLYVLP GNHENNWSQS ATKTFVDIFG NDRFVFKVDS
     LIVVGINCGP FMKMGDGHIK QEDLHWLKST LDSLVIPGTK VLSFNHYPIR PNDLDNWRDY
     ADVLLQYPVI AHINGHYHRW MRYDVGDIEG IMVRALDMGN GNYGYSIVNV TPQWTFVYDK
     QLDKDPVARF ATSNRMKHMA IKENRIGFDE SNVPTGYDVT RVWTDSASIF TRIGFDAENV
     YFATSIGNIR AINKCDGQLR WSVCVPDCAS VFSRPVSLGG KKHFVAAPYC SGILVLESRT
     GSIVRNITSK EGPYVADGVV SPDGKRYIQG GYKRMECRDT TNPAKVIWCY DSIFNYCQAA
     PTIAGDDLVF GAWDTNLRCL DIRTGQLRWY WNNGKTANML GPGNVVPVVT GDKVFVVAPD
     RYMTALDRRT GTQLWRDNSH KYRESLGVSR DGSMVYAKTM DGELVAVDTQ SPKFKELWTI
     DMGLGYEHAP CIVAEDNTGI VYAGSRRGIV TAVDPVAQKV VWSIPLGVSE INGIDIDPST
     GDVWVSLIEG TVFRISRK
//