ID   R7JUQ1_9FIRM            Unreviewed;       219 AA.
AC   R7JUQ1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Histidine kinase-DNA gyrase B-and HSP90-like ATPase {ECO:0000313|EMBL:CDE67689.1};
GN   ORFNames=BN630_00401 {ECO:0000313|EMBL:CDE67689.1};
OS   Blautia sp. CAG:37.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX   NCBI_TaxID=1262757 {ECO:0000313|EMBL:CDE67689.1, ECO:0000313|Proteomes:UP000018204};
RN   [1] {ECO:0000313|EMBL:CDE67689.1, ECO:0000313|Proteomes:UP000018204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:37 {ECO:0000313|Proteomes:UP000018204};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE67689.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBJJ010000295; CDE67689.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7JUQ1; -.
DR   Proteomes; UP000018204; Unassembled WGS sequence.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR   InterPro; IPR039506; SPOB_a.
DR   PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   Pfam; PF14689; SPOB_a; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CDE67689.1};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018204};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          25..78
FT                   /note="SpoOB alpha-helical"
FT                   /evidence="ECO:0000259|Pfam:PF14689"
FT   DOMAIN          119..218
FT                   /note="Sensor histidine kinase NatK C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14501"
SQ   SEQUENCE   219 AA;  25073 MW;  EC14D8C8FE81859E CRC64;
     MAHIPFLSHY LERKNIEYQN QLLARQVEEV QNIYLTMRGW RHDYHNHLQS MKAYVEMGQY
     DKLQEYLGLL ENDLDQVNQL CDSGNVNLDA ILNSKISLAE KNGIRVDYKA VCPANLTVSD
     IDLCALIGNL IDNAVEACEG LADPYIRLYI GVLKNQLYIS VTNATKDTVR KLDSEYITTK
     RGNHGHGLKR INLVVEKYEG YINRQNEPGV FVTEIMLPL
//