ID R7K835_9FIRM Unreviewed; 580 AA.
AC R7K835;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=FAD linked oxidase domain protein {ECO:0000313|EMBL:CDE72499.1};
GN ORFNames=BN810_00135 {ECO:0000313|EMBL:CDE72499.1};
OS Acidaminococcus sp. CAG:917.
OC Bacteria; Bacillota; Negativicutes; Acidaminococcales; Acidaminococcaceae;
OC Acidaminococcus.
OX NCBI_TaxID=1262688 {ECO:0000313|EMBL:CDE72499.1, ECO:0000313|Proteomes:UP000018048};
RN [1] {ECO:0000313|EMBL:CDE72499.1, ECO:0000313|Proteomes:UP000018048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:917 {ECO:0000313|Proteomes:UP000018048};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE72499.1}.
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DR EMBL; CBJM010000048; CDE72499.1; -; Genomic_DNA.
DR AlphaFoldDB; R7K835; -.
DR STRING; 1262688.BN810_00135; -.
DR Proteomes; UP000018048; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:UniProt.
DR GO; GO:0008609; F:alkylglycerone-phosphate synthase activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.30.300.330; -; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.3450; -; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR025650; Alkyl-DHAP_Synthase.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR46568; ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL; 1.
DR PANTHER; PTHR46568:SF1; ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000018048}.
FT DOMAIN 121..307
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT ACT_SITE 487
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625650-1"
FT BINDING 431
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR625650-2"
FT SITE 344
FT /note="Important for enzyme activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR625650-4"
SQ SEQUENCE 580 AA; 66227 MW; 8B442483564B77D1 CRC64;
MSVKPYKGFE PKWVKEPAPS DSYRSIFRWG DPNFVKYPKE SLYKMMKDIF HLTDEDFKQY
DKDIGFDKVE LNIPSKMDKK HIDEFKKIVG EDNVSTSDYD KLSVAYGKTG YDCLRMRQKR
FDSLPDVVLY PSESSEIERI VDYCVKNKIP LYVYGGGSSV TMGVEPVKGG VSLDMRKNFN
KVICFNETDQ TITVQAGMSG PKLEATLNDA VKLFNAKRAY TCGHFPQSFE YSSVGGWVVT
RGAGQNSTYY GKIEDIVLSQ KYATPIGTIS TTKYPREATG PNLNQIMMGS EGAFGVLTEV
TLRVFRFMPK NRKRFSYIFK TWEQAMEAAR EMMQCECGFS SVFRLSDQEE TSLMLRLYNV
DETPLNKLLN VFGYKDMERC LFLGFTDGEA GYSKNVAKNI RKIAKKYGGM SLTGFVCKSW
EKGRFNDPYL RDTLLDFGVM TDTMECSVNW SNMEQVHLDV RKVCKQLPNT IVTTHMSHCY
PQGANLYFIF ITKMSDADAF KKYHSSILDA IQKSGAAMSH HHGIGKMFGP WLEGYLGRNE
FGVFKALKNY FDPEYLMNPG GTIGLDVKEE DKRFLRDDIK
//
