ID R7KLG3_9BURK Unreviewed; 1310 AA.
AC R7KLG3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:CDE76563.1};
GN ORFNames=BN692_01420 {ECO:0000313|EMBL:CDE76563.1};
OS Sutterella sp. CAG:521.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=1262977 {ECO:0000313|EMBL:CDE76563.1, ECO:0000313|Proteomes:UP000018289};
RN [1] {ECO:0000313|EMBL:CDE76563.1, ECO:0000313|Proteomes:UP000018289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:521 {ECO:0000313|Proteomes:UP000018289};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE76563.1}.
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DR EMBL; CBJP010000086; CDE76563.1; -; Genomic_DNA.
DR STRING; 1262977.BN692_01420; -.
DR Proteomes; UP000018289; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:CDE76563.1};
KW Hydrolase {ECO:0000313|EMBL:CDE76563.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018289}.
FT DOMAIN 84..247
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 279..446
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1310 AA; 148744 MW; 9090FC84C7CA5C4B CRC64;
MSGNSLRDQL SGLMQARKQQ AQAQALEAEK KKAARITKEK NKSTEKKEAD ENSASNKANA
KAGVHARLTP APGLPVSQRA KEIIEAIKKN RVLILCGETG SGKTTQLPKL CVLAGRGRKG
KIAHTQPRRI AASSIAKRLA EETGTDLGQW VGFKIRFTDR TDPGAKVKLM TDGILLAETQ
GDPLLKAYDT IIIDEAHERS INIDFLLGYL KGLLKKRPDL KVIVTSATID SERFAKHFSD
EKGQPAPVLT VSGRTYPVEI RYRAPEDEDE TDDKSLMNAI SDACDELTRE GPGDILVFLP
GEREIREAAE TLTRSQPPTT EILPLYARLS AAEQEKVFKT SEKRRIVLST NVAETSITVP
GIHYVVDTGL ARVKRYSYRN KVDQLLVEPV SQASANQRSG RCGRVANGIC IRLYSEEDFA
RRPAFTDSEI MRTNLAAAIL RMKALRLGDV RAFPFVQAPP NRAIVDGISL LKELNALDER
ERLTDIGRAL AKLPVDPKVA RMLLAAKENG SLAEVLIIAS ALSVQDPRER PLDRQEAADN
VHRSMADDKS DFSTFVKLWR YVQNAMDHKE SNRKLTEEFR RKFLSPRRLR EWRDVYRQLK
ELTAELGWQL NDKEATYEQV HTALLSGLLG NLGYKIPDAE PKAAPFLGAR GIKFYIWPGS
PRVKKCGRWI MAAELVETSR LFARTVADVD PQWIEKVGAH LIKKSYSEPH WEKKAGAVMA
MEKGTVYGLT VYGQRKVTYT DKDPALCREL FIREALVNGE FETQAPFFKH NQQLVREIRN
LEHKARRLDV LVDDELIVQF YDSHIPAEVV SAVTFEQWRR KAEKDNPRLL YLSRDELMRH
EASGITTEYF PKAMDMKGVS MALTYHFEPG SPRDGVTLAV PLYALNLVDE VKTQWLVPGM
LKEKVQLLLK SLPQRYRRHC VPLAEYAKGF AQRAADVLGT KPLLQVLCDD IESQCAIRPR
QEDFKLEQLP AHLTMNFKVL DEYGRQIEMG RNLAVLKSEL GGQAQKSFQQ VAAQDSEVSH
ECDQEITQWD FGELPDIMEI KRKGQSLIGH PALVDHDSYC SLEVFDNPDE AARQHQKGLL
RLFKLQLREQ IRYLEKSLKP LQSVQMQAAM LEPMADVFDS FEAMREAVID ASLNQCAMTE
PLPVNAEQFE SRRQEAKGKL NLIAQDISRL LSQIISDTAL VIKKLKSCSD KWVLEDIEHQ
LKSLFFKDFL LKIGYLHLSH YPRYLQAILV RLEKRRDEPE KDAQKMRDIS RFVTMYEREL
ASRKGVADNR LEEFRWMIEE LRVSLFAQKL RTPMPVSVKR LDKVWSSIKY
//
