ID R7KSN2_9BURK Unreviewed; 892 AA.
AC R7KSN2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Acyl-CoA synthetase (NDP forming) {ECO:0000313|EMBL:CDE77977.1};
GN ORFNames=BN692_00441 {ECO:0000313|EMBL:CDE77977.1};
OS Sutterella sp. CAG:521.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=1262977 {ECO:0000313|EMBL:CDE77977.1, ECO:0000313|Proteomes:UP000018289};
RN [1] {ECO:0000313|EMBL:CDE77977.1, ECO:0000313|Proteomes:UP000018289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:521 {ECO:0000313|Proteomes:UP000018289};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE77977.1}.
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DR EMBL; CBJP010000146; CDE77977.1; -; Genomic_DNA.
DR AlphaFoldDB; R7KSN2; -.
DR STRING; 1262977.BN692_00441; -.
DR Proteomes; UP000018289; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF13302; Acetyltransf_3; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000018289}.
FT DOMAIN 495..532
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 736..892
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 892 AA; 97333 MW; E19DC466375BBB55 CRC64;
MDTSHQLRAA LAPESIAVIG ASDREASRGA PLWKNLISAG FSGRIYPVNP KYRYLGDIPC
YPSIKAIEDH IDLAILAVPT KTIESVLEDI ASHGTHWIAL APSDASVTSD SNWQAKIVNK
AHALGLRLIG TDCLGIMRPS MNLNASYWSE LPLAGNVGFA AQSGVIGTSL LATKRIRDIG
FSTLINTGDE IDVSMSEVVD FLAQDKETGV IVLHIEGIRN PREFFSAVRE AAKHKPVIVL
RGGKSLQASQ LLASRMGVPA GDDKVFNALL ERAGAIRVYG LEEMLSAIEI FGQKRLPRSN
RVGIISNGSG FGVLAADAAS ECDVKIATLS RTTTEKLHKI FDNPLPMTNP VDLWADADPR
RIKLAVDALN KDENVDAIII VTAPTFAAPL ERVCDAIAYA TDASYKPIIT AWIGESQTIA
AKKRLKDHPI TVLKSPESAI KAFSWMAHYA QSRRYLAATI ASESDPLPAD ERAIRNILEE
NKSNECYSLN ELQTKKLLAC LGLTAATGIL VQSPIEAVNA AKNLGFPVVI KAIAKGVIHK
SNVGGVALDL KTEEDVLKAS QSILESVKNR APYAQLEGLY IQRYIRQPHG REVKITVHTD
SRFGPVISFG AGGHMGDIYK DDVCELLPLT KPLAAALIEK PTVSTYLGDF RGMPAANKEA
LAQILMRISK LVTDFPLIRD LTIDPLLVDE GGCIVLDAHI GISPNNLDKD ALASHLTLAP
EPSIDSAWRD IKGGQVSLRS IHAQDYDSLR DFLKRLSPQT TYLRLHISSN ELAREKLIEL
TNIDYNREVA IVACDTEEPD LIHGVARFKR MPGTSFAEFG VVVEDEWQRR GLASLLMKEL
IEQAKIMKLT VLIGYVLRGN DGMFALMDSL GFVRHEDETL DDAFVVYTLN LE
//
