ID   R7L1E6_9FIRM            Unreviewed;       298 AA.
AC   R7L1E6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=S-adenosylmethionine-dependent methyltransferase domain-containing protein {ECO:0000259|Pfam:PF10672};
GN   ORFNames=BN622_02275 {ECO:0000313|EMBL:CDE81831.1};
OS   Ruminococcus sp. CAG:353.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262955 {ECO:0000313|EMBL:CDE81831.1, ECO:0000313|Proteomes:UP000017936};
RN   [1] {ECO:0000313|EMBL:CDE81831.1, ECO:0000313|Proteomes:UP000017936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:353 {ECO:0000313|Proteomes:UP000017936};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE81831.1}.
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DR   EMBL; CBJQ010000159; CDE81831.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7L1E6; -.
DR   Proteomes; UP000017936; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR019614; SAM-dep_methyl-trfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43042:SF2; SAM-DEPENDENT METHYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF10672; Methyltrans_SAM; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017936};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          123..209
FT                   /note="S-adenosylmethionine-dependent methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF10672"
SQ   SEQUENCE   298 AA;  33161 MW;  EC469CF1AAC5F75E CRC64;
     MRCADRWHDY RLVDCTCSEK LEYWGKVSLV RPDPQVIWKT AKKTPVWDKA DGHYHRSEKG
     GGQWSFTRRL PESWQIGYDL ITGQKLTFNI RPTGFKHTGL FPEQAVNWDF MAKMISEGIA
     SGREVNVLNL FAYTGGATLA CAAAGASVCH VDASKGMVQW ARDNAASSGL SDRPIRWIVD
     DCEKFVAREI KRGRRYDAVI MDPPSYGRGP NQEVWKLEDC VYDLVDLCVG VLSDDPLFFL
     LNSYTTGLSP SVMAYIIGET VGSRYKGKVS ADEIGLPVET GSYALPCGST AMFTAENI
//