ID R7LUD4_9FUSO Unreviewed; 431 AA.
AC R7LUD4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Peptidase metallopeptidases {ECO:0000313|EMBL:CDE92135.1};
GN ORFNames=BN791_00960 {ECO:0000313|EMBL:CDE92135.1};
OS Fusobacterium sp. CAG:815.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=1262901 {ECO:0000313|EMBL:CDE92135.1, ECO:0000313|Proteomes:UP000018095};
RN [1] {ECO:0000313|EMBL:CDE92135.1, ECO:0000313|Proteomes:UP000018095}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:815 {ECO:0000313|Proteomes:UP000018095};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE92135.1}.
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DR EMBL; CBJW010000033; CDE92135.1; -; Genomic_DNA.
DR AlphaFoldDB; R7LUD4; -.
DR STRING; 1262901.BN791_00960; -.
DR Proteomes; UP000018095; Unassembled WGS sequence.
DR GO; GO:0031012; C:extracellular matrix; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR001818; Pept_M10_metallopeptidase.
DR InterPro; IPR006026; Peptidase_Metallo.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10201; MATRIX METALLOPROTEINASE; 1.
DR PANTHER; PTHR10201:SF272; ZNMC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00413; Peptidase_M10; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 3.
DR SMART; SM00235; ZnMc; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000018095};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT REPEAT 25..58
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 126..279
FT /note="Peptidase metallopeptidase"
FT /evidence="ECO:0000259|SMART:SM00235"
FT REPEAT 345..378
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 382..415
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 431 AA; 49952 MW; 54CB23C059ECD33D CRC64;
MRKVLLFILF VVLVVYMLYK SPFSASYYYN KAKALYSAGQ YEQSLPLFEK SLFSDPKNIL
TRFYYVLALS KSKPTYSVQK KLYEIGNSKI NDEAKKYARY QAVYLRHNLL IGVENNYIFN
AVAGNDIIRW DINSFPLKIY YKNVKSVPAY YHENIDKALS QWTQRTNFVK FVQTKDEKDA
NIVIKFSDIS DNSCKSENCK FAIAYTDPVI TSSGVLEKMN LTFFKTNPRH ELFSPLEVYN
TALHEIGHTL GLMGHSDNPE DLMYASNDNS KNIYALYRSD FQYLTSRDLK TLALLYRLEP
TISNVKGLHS ENFYYPPLIM GSEDARLLKK LEEYQKYIQK YPNFAAGYIN IASIYVDMGD
FDLALNALNS ASNLAQNEDE NYMVAYNRAI IYYNKRDYNN ALNYAKQAKS IRPSNNIDEL
INDIYKIKNA S
//
