ID   R7MIS9_9FIRM            Unreviewed;       379 AA.
AC   R7MIS9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=NADPH-dependent butanol dehydrogenase {ECO:0000313|EMBL:CDF01019.1};
GN   ORFNames=BN739_00985 {ECO:0000313|EMBL:CDF01019.1};
OS   Ruminococcus sp. CAG:624.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262965 {ECO:0000313|EMBL:CDF01019.1, ECO:0000313|Proteomes:UP000017977};
RN   [1] {ECO:0000313|EMBL:CDF01019.1, ECO:0000313|Proteomes:UP000017977}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:624 {ECO:0000313|Proteomes:UP000017977};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDF01019.1}.
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DR   EMBL; CBKC010000138; CDF01019.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7MIS9; -.
DR   STRING; 1262965.BN739_00985; -.
DR   Proteomes; UP000017977; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd08179; NADPH_BDH; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR   InterPro; IPR034802; NADPH_BDH.
DR   PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017977}.
FT   DOMAIN          1..364
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   379 AA;  41501 MW;  C6E6FBDE48CBA8F6 CRC64;
     MICVGGGSMK RFGFLDKAQS YLKEAGMEVS IFDGIEPDPS VETVMKGADA MMKFQPDWIV
     AIGGGSPIDA AKAMWIKYEY PDCTFEDMCK VFGIPELRKK AHFCAVSSTS GTATEVTAFS
     IITDYNKGIK YPIADFEITP DVAIVDPELA ETMPKKLVAH TGMDAMTHAI EAYVSTANCD
     YTDPLAIHAI EMIMKDLTAS YNGDMEARDR MHNAQCLAGM AFSNALLGIV HSMAHKTGAA
     FADYGAHIIH GAANAMYLPK VIAFNAKDET AKKRYGVIVD YMGIADKNAS DDDKVSALIT
     YLRKMNDELN IPHCIKNYGA DSYPVENGFV PENVFLERLH DIAVNAIGDA CTGSNPRQPS
     VEEMEKLLKC CYYDTEVDF
//