ID   R7N9I3_9FIRM            Unreviewed;      2994 AA.
AC   R7N9I3;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Surfactin synthetase B {ECO:0000313|EMBL:CDF08777.1};
GN   ORFNames=BN816_00756 {ECO:0000313|EMBL:CDF08777.1};
OS   Firmicutes bacterium CAG:95.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1262988 {ECO:0000313|EMBL:CDF08777.1, ECO:0000313|Proteomes:UP000018182};
RN   [1] {ECO:0000313|EMBL:CDF08777.1, ECO:0000313|Proteomes:UP000018182}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:95 {ECO:0000313|Proteomes:UP000018182};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDF08777.1}.
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DR   EMBL; CBKF010000251; CDF08777.1; -; Genomic_DNA.
DR   STRING; 1262988.BN816_00756; -.
DR   Proteomes; UP000018182; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   CDD; cd05930; A_NRPS; 3.
DR   Gene3D; 3.30.300.30; -; 3.
DR   Gene3D; 3.40.50.980; -; 4.
DR   Gene3D; 1.10.1200.10; ACP-like; 3.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 3.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 3.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00668; Condensation; 2.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   Pfam; PF00550; PP-binding; 3.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR   SUPFAM; SSF47336; ACP-like; 3.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00455; AMP_BINDING; 2.
DR   PROSITE; PS50075; CARRIER; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018182}.
FT   DOMAIN          514..589
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          1520..1595
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          2517..2591
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   2994 AA;  337180 MW;  0D50245E5A461046 CRC64;
     MSDINEKSGF AFTFQPVTKL FEEQVRLHPE KCAVASGKES FTYAELNERA NKIAHSLIGK
     GAGREIIVGV VLERCCDFYA VRQGILKSGS AFAVASPDYP DDRIQFIFED AGVPLLITTK
     EIAKERKELF DKLPCKVLLL EELLQHPDTE NPDVEIREHD LCYCIYTSGS TGKPKGVMIE
     HLNLANFVNP DPKNAETYGY VSRGSVSLSM AAMTFDVSVL EEFIPLTNGL TAVIATDEEI
     QNPMMLGDLI VKNHVDIMTT TPTYLSNMID LPQLKEAASR IRVYDVGAEA FPPALYDKIR
     SVNPDAYIMN GYGPTETTIS CTMKVISDSK NITIGTPNGN VRVYVVDKEN RILPDGETGE
     LVVAGLGVGR GYINLPDKTA AVFINLNGER AYKTGDLARI TPEGEIEFFG RMDNQIKLRG
     LRIELGEIEE VINSYEGIVT SITVPVDNKY LCCYFLADHK IDTGELSDYA AESLAHYMVP
     DVFIQMDRMP VTANGKIDKS ALPKPISQPK NLKEPETPMQ KRIFEIVANV VENDFFGIDT
     SFYKAGLSSI SAMKLCILIS DEFGVTVKTS DIHENNTVEK LENYVMLAPK IRTYEKREVY
     PLTGSQKGIF VECSKNPEST VYNIPFLFEL DRATDVQKLS DAVAQMVNAH SYLLTEVFLN
     DQGEMVQRPG TENFVPDVIE TTNEQFEALK KELVRPFRLE KGRLFRAQIY VTEDRKYLFT
     DFHHIIADGN SYDIIFKDIN RAYVGEKLEK ETYTGFDAAL DEEQQMQEGK YKKAEKYYDS
     VFGEVETESL PFPDVTGKAP EKGYLERKLT VAEDKILSCC EKLGVTPNIL FTGVFGILMS
     RYSNSDDSLF STIYNGRNDS RLENTVCMLV KTLPVYCKFE AKTTIQAYMT ELSEQLLSSM
     ANDIFPFSDI CAKYGFNSDL TFAYQAELSD DYPIGDTVAR GHDLSLDMAK MPLLIQVREY
     NNEYVLTAEF RSDRYSDAFV AGMLEAYEAA MDSMLKNKYV SEVSILSENA VKKIAEFNDT
     ACKYDRTKTI SDRFTEMVQT IPDHTAVVFK DKKYTYKELD EISDRLGKYI ASRGIGTEDV
     VSILIPRCEY MAIAPMGVIK AGAAYQPLDP SYPKDRLMYM LEDSAAKLLI ADRELLHLVD
     GYQGPVLYTD EIMQLEDVDV ELKKPQLHDL FILLYTSGST GVPKGCMLEY GNITAFCHWY
     RKYYSIDPDC KVAAYASFGF DASMMDTYGA ITNGAELHII PEEIRLDFIG LQKYFEENGI
     THSFMTTQVG RQFALEMECR SLRYLSVGGE KLVPCEPPKG YRFFNVYGPT ETTILVTAFE
     VDKYYPNIPI GKALDNVKLY ITDKSGHMLP YGACGELMIS GFQVSRGYLN KPEKTAEVYT
     KNIYDDTEGY EVLYHSGDIA RYLPDGNVQI IGRKDSQVKI RGFRIELSEV EEVIRRYQGI
     KDATVVAFDD PNGGKYIVAY VVSDSEVDIN GLNDFIKETK PAYMVPAVTM QIDKIPLNQN
     QKVNKKALPV PERKIEEIIE PKNETQQKLF DCIADVLGYK EFGITTDIYE AGLTSISAIK
     LNILISKAFD IVIKTSDIKS HPTIELLEGF VKTAGKETKR EVQENYPLTN TQEGIFIECT
     ANMGSTIYNI PYLLKLNKKV DLDRLAAAID STIEAHPYLK TRLFMDENGD VLQKRDDGLT
     CKTQIINGMN RETLVRPYML FNEQLFRFEI YRTCDGNYLF LDIHHIIADG TSLGIILNDI
     NRAYSGEKLE AETYTSYDLA LDNRDALKSD VYKNAENYYK SVFENKGGSI NFYPDKNGPV
     PTAETYHREV TEVSVQEVKD FCKKHGITEN VFFISVFGLT LGKYNFRKDA VFTTIYHGRN
     DSRLSETVGM LVKTLPVYTD FAGSLKDGLL AVQQQLINSM NNDIYPFSQI SHEFSIKADA
     MVIYQGDNFA FDTIGGEYAQ EEPISLNAAK APVSISISID RNKFVFEIEY RGDMYYEDTM
     KYLADNLEIA AGGILREQEP DDIKLLFEEK TTMEDDPEHA GKTFVDLFRE AVEKYPDRPA
     VRDGKGEITY RELDRMSDYV AQKLTENGFG REQAAGILCG RTREFAVAYV GVMKAGGAYV
     PLDPEYPQSR IEYMLKDSGA DNLLVINQYR ELVSFYDGNI LSLDEVAEAS KDFTLSVELT
     SPKPENLAYM IYTSGSTGKP KGVMLEQRNL LNLIEYIRLT RKTSPDDIVA EFASFCFDAS
     VIDLFAPLTA GALLYIFPED IRKDAVAVAK CIQDQKITSA TFPTQMGELV TELLEDAPCL
     KFVTLGGEKF KHYRNRTYQM INGYGPTENT VSSTEFWVDK QYDNIPIGKS QRNVRSYVVS
     EDLKRLPVGA SGELCHAGRQ IARGYHNLPE KTASVFVENP YSVCEDDKRL YRTGDMVRMK
     GDGNIEYIGR IDSQVKIRGY RVELGEIEGA VLKHELVKNS AVTVVEKGGN KYITAYYTGE
     SIPDEELKTF LEPLIPDYMM PSFFVHIDEM PVTPGGKIDK KALPVPEVAV NNTSYVEPVT
     MVQKTLCEIF EKALGTEKVG IEDNFFDLGG SSLTASKVAV MCLSRNISIV YADVFKHPTV
     RELAEIVDDQ ASAESPQSNN EFSDYNYNRI QSVISGNVEE NADRITKEEL GDIMITGATG
     FLGIHILKAY LDNYDGKVYC LVRKGSYESM EKRMMHMLMY YFDNPCEELF KDRIVCVDGD
     ITSKEQVESF GAYKFRTLIN CAACVKHFAA GDVLQKINVH GVENLIEFCK NNGRRLIQIS
     TVSVAGEGSN GVPPMDRVFS ENDLYIGQSI TNEYIRTKFL AERAVLEAVS GGLDAKIIRV
     GNLMSRNSDG EFQINFITNG FLRSLRGYKA IGKFPMGGMH EVAELSPIDS TALAVLKLVQ
     TDRRFTVFHA CNSHHIYMAD LIYAMRNYGF KLDIVKDEEF EEAVKEFAKN GNDSDAVSGL
     IAYTSHNENE IYTMEYSNRF TAQVLYRLDY KWPVTDDRYL ESAIEALDRL AFFD
//