ID R7NAZ9_9FIRM Unreviewed; 384 AA.
AC R7NAZ9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Ribosomal large subunit pseudouridine synthase C {ECO:0000313|EMBL:CDF09950.1};
GN ORFNames=BN774_00669 {ECO:0000313|EMBL:CDF09950.1};
OS Eubacterium sp. CAG:76.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262892 {ECO:0000313|EMBL:CDF09950.1, ECO:0000313|Proteomes:UP000018156};
RN [1] {ECO:0000313|EMBL:CDF09950.1, ECO:0000313|Proteomes:UP000018156}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:76 {ECO:0000313|Proteomes:UP000018156};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC {ECO:0000256|ARBA:ARBA00010876}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF09950.1}.
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DR EMBL; CBKG010000059; CDF09950.1; -; Genomic_DNA.
DR AlphaFoldDB; R7NAZ9; -.
DR Proteomes; UP000018156; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0120159; F:rRNA pseudouridine synthase activity; IEA:UniProt.
DR GO; GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IEA:UniProt.
DR CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR PANTHER; PTHR21600:SF92; 21S RRNA PSEUDOURIDINE(2819) SYNTHASE; 1.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR Pfam; PF01479; S4; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 13..73
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
FT REGION 79..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 384 AA; 43601 MW; 0E3F7A79EC798775 CRC64;
MKELIIDKLG DNQRLDKYLS KYLSAASKSF IYKMLRKKNI TLNDKKADGS EKLQSGDSVK
IFFSDETLNK FSEGKSCISN AGSRQTNNMT DKAADNTANE PAVRTDGKHT DSTADKYSYT
ASKKGLSVDY EKIYRPLDIV YEDENVLFIN KPVGMLSQKA DKNDCSLVEY ITAYLLHNNS
LTYEDLAMFT PSICNRLDRN TSGIIAAGKT MKGLQELSSH FKERTLTKYY ICIVAGKVDK
RQLIKGYLYK DKKLNKVTIC QTLPKGRDTS EYLPIETEYI PVAYSDNATL LKVHLITGRS
HQIRAHLASI NHPLAGDYKY GKASFNRRFT DKYNCKSQLL HSYELNIPDM DIHIHTDIPD
IFLNVLKGEN IWQPGIQEVL EALH
//
