ID R7NBJ6_9MOLU Unreviewed; 287 AA.
AC R7NBJ6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=ATP-dependent DNA ligase family profile domain-containing protein {ECO:0000259|Pfam:PF01068};
GN ORFNames=BN778_00297 {ECO:0000313|EMBL:CDF10829.1};
OS Mycoplasma sp. CAG:776.
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=1262906 {ECO:0000313|EMBL:CDF10829.1, ECO:0000313|Proteomes:UP000018174};
RN [1] {ECO:0000313|EMBL:CDF10829.1, ECO:0000313|Proteomes:UP000018174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:776 {ECO:0000313|Proteomes:UP000018174};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF10829.1}.
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DR EMBL; CBKH010000009; CDF10829.1; -; Genomic_DNA.
DR AlphaFoldDB; R7NBJ6; -.
DR STRING; 1262906.BN778_00297; -.
DR Proteomes; UP000018174; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07906; Adenylation_DNA_ligase_LigD_LigC; 1.
DR Gene3D; 3.30.1490.70; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR45674:SF15; DNA LIGASE (ATP); 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018174}.
FT DOMAIN 19..192
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|Pfam:PF01068"
SQ SEQUENCE 287 AA; 34263 MW; 88A23B3E8F1AE7C1 CRC64;
MFHNYKLRPM LLWEKSKIFQ DSNYLYEIKF DGFRAFIYVS RKKFVILSRN GNDVTKKYPE
LSEMQKIVGE HEVIFDGEII TTLNGLPNFS LLQKRSRSKK ITDKIMEDIP VSFIAFDILY
DNKDLTKNSL AKRKEYLNHY EDTLYFIKSK VYFDGKALFK LIKKVGLEGV VAKFKKSQYF
CGERTKEWVK IKNIKVDQFL VHGYQEKTNT FTLFLGEYRN QQFYFVGKVS VHKKHELIDQ
LKRLKKTENM FINLDEKAFY VFPKIEVRVH YLEKSKAGIL RHAVLEY
//
