ID   R7NCI1_9FIRM            Unreviewed;       461 AA.
AC   R7NCI1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Glutamate synthase (NADPH) {ECO:0000313|EMBL:CDF10251.1};
GN   ORFNames=BN774_00943 {ECO:0000313|EMBL:CDF10251.1};
OS   Eubacterium sp. CAG:76.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=1262892 {ECO:0000313|EMBL:CDF10251.1, ECO:0000313|Proteomes:UP000018156};
RN   [1] {ECO:0000313|EMBL:CDF10251.1, ECO:0000313|Proteomes:UP000018156}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:76 {ECO:0000313|Proteomes:UP000018156};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDF10251.1}.
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DR   EMBL; CBKG010000065; CDF10251.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7NCI1; -.
DR   Proteomes; UP000018156; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006004; SudA-like.
DR   NCBIfam; TIGR01316; gltA; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          17..127
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          139..447
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   461 AA;  49559 MW;  814F64D89CC06AD9 CRC64;
     MDVMKKVPVR EQAPDVRNKN FDEVCLGYNA EEAQEEATRC LNCKNAKCVQ GCPVSINIPE
     FIHNVKEGNF EEAYKVIGKS SALPAVCGRV CPQETQCEGQ CIRGIKGEAI SIGKLERFVA
     DWARENNVSP EMPTEKKGKK VAVIGSGPSG LTCAGDLAKM GYDVTIFEAL HEAGGVLVYG
     IPEFRLPKKT VVASEIENVK KLGVKIETNV VIGKSMTIDQ LINEEGFDAV FIGSGAGLPR
     FMGIPGENAN EVFSANEYLT RSNLMKAFRE DYDTPIARFK KVAVVGGGNV AMDAARTALR
     LGAEVHIVYR RSEEELPARA EEVHHAKEEG IIFDLLTNPT EVLTDDKGNV TGIKCVKMEL
     GEPDASGRRK PVEVPDSEFV MDLDAVIMSL GTSPNPLISS TTKGLEINKR KCIVAEEANG
     QTSKEGVYAG GDAVTGAATV ILAMGAGKAA AKGIDEYLSN K
//