ID R7ND22_9MOLU Unreviewed; 1120 AA.
AC R7ND22;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Pyruvate-flavodoxin oxidoreductase {ECO:0000313|EMBL:CDF11354.1};
GN ORFNames=BN778_00539 {ECO:0000313|EMBL:CDF11354.1};
OS Mycoplasma sp. CAG:776.
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=1262906 {ECO:0000313|EMBL:CDF11354.1, ECO:0000313|Proteomes:UP000018174};
RN [1] {ECO:0000313|EMBL:CDF11354.1, ECO:0000313|Proteomes:UP000018174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:776 {ECO:0000313|Proteomes:UP000018174};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pyruvate:ferredoxin/flavodoxin
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00009032}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF11354.1}.
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DR EMBL; CBKH010000021; CDF11354.1; -; Genomic_DNA.
DR AlphaFoldDB; R7ND22; -.
DR STRING; 1262906.BN778_00539; -.
DR Proteomes; UP000018174; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0022900; P:electron transport chain; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR019456; Pyrv-flavodox_OxRtase_EKR.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR011895; Pyrv_flavodox_OxRed.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; TIGR02176; pyruv_ox_red; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF10371; EKR; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01558; POR; 1.
DR Pfam; PF01855; POR_N; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SMART; SM00890; EKR; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Pyruvate {ECO:0000313|EMBL:CDF11354.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018174};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 656..686
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 701..730
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 1120 AA; 124733 MW; 3431CB8F4968778F CRC64;
MKICDGNKAC SDIAYYFSEI SSIYPITPSS PMASNIDLLS HDKLNLFDSP VKLVEMQSEA
GAAGTFHGAL ISGSLASTFT ASQGLLLMIP NMYKIAGEML PGVIHVAART IATNALSIFG
DHSDIYATRA TGFAILASSN VYDAQNLATV AHLSAIEGSI PFLHFFDGFR TSHEISSIKE
LKESELKKII PWDKIEEFKN RALNVGAGIQ KGMAMNEDIF FQTQEARNPN YNMLPDIVNK
YMEKINNIMG TSYKPFTFYG SKEAENIIIA MGSITDTIKL VIDEELKKGK KIGLITVHLY
RPFSPKYLLN VLPKTVKNIA VLDRTKEAGA NGEPLYLDIV NALKEEKVNI VGGRFGLSSK
NTTPADVKSI YTMLEENPKN NFTVGITDDL TFTSLSKEEY KIKLNAKEFL IYGYGSDGCV
SASKDILKIM GKNNKYVNGY FSYDSKKSGG VTVSNLRISE EEINAPFYVT NPSLIVVTKD
EYFKKYSMIK DIAENGMIII NTNKNEKEIN ELLSLEDIEI IKNKKVKVIT INADEIATKN
GIKGKISKII EMIILNKLEI PNAYELLKES IETSFKTKGE NIIKSNISAI EEALVNLKEI
KIEELPFKPT EKDLDVFSKI NKRLGDELTV SEVASLKDGT FPAGLSRYEK RHVNKVAPKW
IKENCTMCGR CSFVCPHAVI RTFVTKDDKG IPFLTNKEYT YQVLVSEADC TECGLCISEC
PGKNGKKALE FGPVDLELQK EANQYFNDYE NPELLNKFTI PGASLCKPRF EFSGACAGCG
ETPYINLITR LYGDELVIAN ATGCSSIYGG SVPTTPYTIP WANSLFEDNA EFALGMHLSY
QSKRNLIINI MKNELDNVSS EVKDLFVEFL NHSNDFKITM DIKNKLSNLE IPSKLKGLLN
YLPARTVLAI GGDGWAYDIG FGGLDHVLST NENIKVLVLD TEVYSNTGGQ ASKSSKLGAV
AEFADFGKKT AKKDLFRIAM SYPNCYVASI SLGANMMHSI KVMKEAMEHN GPAIIIAYSP
CIEQGIKTGM SHSIEEERLA SEVGYTLLMR YNPNEEKLYM DNKEPNFDKY EEFLDNEVRY
NALKIKDQEL AKELLSKQIE NAKKRYSYYQ ELSQKNTSQN
//
