ID R7P8M7_9BACT Unreviewed; 372 AA.
AC R7P8M7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN ORFNames=BN736_01786 {ECO:0000313|EMBL:CDF22059.1};
OS Prevotella sp. CAG:617.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262933 {ECO:0000313|EMBL:CDF22059.1, ECO:0000313|Proteomes:UP000018057};
RN [1] {ECO:0000313|EMBL:CDF22059.1, ECO:0000313|Proteomes:UP000018057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:617 {ECO:0000313|Proteomes:UP000018057};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF22059.1}.
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DR EMBL; CBKM010000109; CDF22059.1; -; Genomic_DNA.
DR AlphaFoldDB; R7P8M7; -.
DR STRING; 1262933.BN736_01786; -.
DR Proteomes; UP000018057; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF23; MULTIDRUG RESISTANCE PROTEIN MEXA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018057}.
FT DOMAIN 54..281
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 97..162
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 372 AA; 40536 MW; 5BB3A98DC64D7974 CRC64;
MNMKSSIYSL LLCLPLLCGC GGKPQKTVGE AYKLLTVTRG DHMLQSRFPA TLQGRQAVEV
RPQVSGTITA IRINEGDVVR KGQVLFVIDQ VPYQAALRSA QANLKSAQAK LRTARLTARS
KEQLYKEKVV SDFDLQTARN ELQEAEAALA QAQAELTKAS NDLSYTEVKS PVDGVASMIP
YRVGALVSSS IEEPLVTVSD DAEVFAYFSM DENQVLDLIQ QYGSLQEAKS KIPPVSLQLS
NGTDYSVRGR IDAIGGTVEQ TMGTVSLRAV FSNPRHLLRH GGSATIIMPT AMRNCISIPQ
SATYELQERI FVWKVVDGKT KSTPISVYKY NDGVNYVVLS GLKEGDVIIA EGAGLVREDT
PINTQQKSSS KN
//
