ID R7QGA9_CHOCR Unreviewed; 657 AA.
AC R7QGA9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=CHC_T00008642001 {ECO:0000313|EMBL:CDF36818.1};
OS Chondrus crispus (Carrageen Irish moss) (Polymorpha crispa).
OC Eukaryota; Rhodophyta; Florideophyceae; Rhodymeniophycidae; Gigartinales;
OC Gigartinaceae; Chondrus.
OX NCBI_TaxID=2769 {ECO:0000313|EMBL:CDF36818.1, ECO:0000313|Proteomes:UP000012073};
RN [1] {ECO:0000313|Proteomes:UP000012073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Stackhouse {ECO:0000313|Proteomes:UP000012073};
RX PubMed=23503846; DOI=10.1073/pnas.1221259110;
RA Collen J., Porcel B., Carre W., Ball S.G., Chaparro C., Tonon T.,
RA Barbeyron T., Michel G., Noel B., Valentin K., Elias M., Artiguenave F.,
RA Arun A., Aury J.M., Barbosa-Neto J.F., Bothwell J.H., Bouget F.Y.,
RA Brillet L., Cabello-Hurtado F., Capella-Gutierrez S., Charrier B.,
RA Cladiere L., Cock J.M., Coelho S.M., Colleoni C., Czjzek M., Da Silva C.,
RA Delage L., Denoeud F., Deschamps P., Dittami S.M., Gabaldon T.,
RA Gachon C.M., Groisillier A., Herve C., Jabbari K., Katinka M., Kloareg B.,
RA Kowalczyk N., Labadie K., Leblanc C., Lopez P.J., McLachlan D.H.,
RA Meslet-Cladiere L., Moustafa A., Nehr Z., Nyvall Collen P., Panaud O.,
RA Partensky F., Poulain J., Rensing S.A., Rousvoal S., Samson G.,
RA Symeonidi A., Weissenbach J., Zambounis A., Wincker P., Boyen C.;
RT "Genome structure and metabolic features in the red seaweed Chondrus
RT crispus shed light on evolution of the Archaeplastida.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:5247-5252(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR EMBL; HG001804; CDF36818.1; -; Genomic_DNA.
DR RefSeq; XP_005716637.1; XM_005716580.1.
DR AlphaFoldDB; R7QGA9; -.
DR EnsemblPlants; CDF36818; CDF36818; CHC_T00008642001.
DR GeneID; 17324355; -.
DR Gramene; CDF36818; CDF36818; CHC_T00008642001.
DR KEGG; ccp:CHC_T00008642001; -.
DR OrthoDB; 909349at2759; -.
DR PhylomeDB; R7QGA9; -.
DR Proteomes; UP000012073; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044, ECO:0000313|EMBL:CDF36818.1};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000012073}.
FT DOMAIN 527..570
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
SQ SEQUENCE 657 AA; 74081 MW; 5E1436BE70D8BB93 CRC64;
MEITAENERY DEISNFQDAR YVSASEAAWR LFSFDIVDRN PPVVRLAVHL PNHHTVYPRA
TLRRRNVSSE EEAYDFSGTG VNVVGRIYTV SRREGERYFL RLLLTQVPGA TSFQNLRNID
GEQCTRFRQA CLRLGLLADD AEWKHAIRDS LRSSFVPLSH LFATILAHCQ PSDPLSLWND
HLDMFLTDIR NRARGQPIRR QQFRDDHHAT SYVLREVQEA LQTMRSDWTL ANFGLPLPDD
SLPALEQQNE IETPEARAQH GRLFFLDAPG GTGKKFVLSA IQDFLRTRRK QFIAVATSAV
AAVLLDGGRT AHSVFKVPIP VSAESTCSFS ANSDTGRTLQ QVDLIIWDEI VMCHRHCIET
VDRYLRDLMQ TDRPFGGKFL VLAGDFRQIL PVVPGGSRGQ IVSPCVKASP LYRECRFLRL
TENMRLAALR ADPAVDVEAL NFPEFLLSSV AFEHTIRNLC LKVFQGIRDN HTDPAWLTKR
VILTTKNRPL EEVNEVIGNM IPGPCRTYLS ADKVESEDTN ALFYPTEMLN TLTAVSALSD
HNLKLKKGFI VMLLRNVDPA TGHVNGARYV TENMTNNLLF LRVTTGSHQG NRLCLPRMPC
GPGDDNFPIP GFTRTQFPIR TCFAITTNKA QGQSFGGCIG LDLRDHCFSY GQLYVAL
//
