ID R7QZ23_9FIRM Unreviewed; 330 AA.
AC R7QZ23;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:CDF42923.1};
GN ORFNames=BN520_02017 {ECO:0000313|EMBL:CDF42923.1};
OS Roseburia sp. CAG:182.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262942 {ECO:0000313|EMBL:CDF42923.1, ECO:0000313|Proteomes:UP000018104};
RN [1] {ECO:0000313|EMBL:CDF42923.1, ECO:0000313|Proteomes:UP000018104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:182 {ECO:0000313|Proteomes:UP000018104};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF42923.1}.
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DR EMBL; CBKT010000249; CDF42923.1; -; Genomic_DNA.
DR AlphaFoldDB; R7QZ23; -.
DR STRING; 1262942.BN520_02017; -.
DR Proteomes; UP000018104; Unassembled WGS sequence.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR020007; N-AcNeuraminate_synthase.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR NCBIfam; TIGR03569; NeuB_NnaB; 1.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018104}.
FT DOMAIN 277..330
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 330 AA; 36353 MW; AACD5594158E253E CRC64;
MKTIIIAEAG VNHNGDMDLA KKLIDEAKKA GADFVKFQTA VDCTSKYAPK AEYQKRETGA
DETQLEMAKK LRLKLEQHYE LYEYCNSIGM SYLSTAFDID SVHFLDSLDL PFFKIPSGEI
TNLPYLLEIA ATKKPVVMST GMAEMDEIAT AIDILKENGT SEITLLQCHT DYPTAMENVN
LNAMLTLKNA FHLPVGLSDH SVGIEVPIAA VAMGATVIEK HFTLDRTMIG PDHKASIEPD
ELKAMVSAIR NIEVALGDGK KICSPAERPN IIVARKSIVA KRDIKKGEIL TEENITTKRP
GNGISAMKWF DVLGTKAIRD FGEDELICTE
//
