ID R7R5G5_9FIRM Unreviewed; 696 AA.
AC R7R5G5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Putative cache domain protein {ECO:0000313|EMBL:CDF46157.1};
GN ORFNames=BN450_02559 {ECO:0000313|EMBL:CDF46157.1};
OS Roseburia sp. CAG:100.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262940 {ECO:0000313|EMBL:CDF46157.1, ECO:0000313|Proteomes:UP000018092};
RN [1] {ECO:0000313|EMBL:CDF46157.1, ECO:0000313|Proteomes:UP000018092}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:100 {ECO:0000313|Proteomes:UP000018092};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF46157.1}.
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DR EMBL; CBKV010000253; CDF46157.1; -; Genomic_DNA.
DR AlphaFoldDB; R7R5G5; -.
DR Proteomes; UP000018092; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018092};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 333..389
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 401..670
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 648..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 483..523
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 696 AA; 76568 MW; B655A5327DAD1E71 CRC64;
MKSIRTKIIM GILFCSLLTA GIIACLAIVN SSQMASVDTA AKSQLSGEVF AGEINSTISR
IEQSVNTLSD AVMQDFDYAA FKKSKDYADQ YTKQIEKEAV NFASHTDGAV TAYVRYNPQY
SNPTSGIFMS RNSTDENFTL LTPTDFSMYD ASDIAHVGWY YQPVEAGEPL WMEPYLNENV
NIYMISYVIP LYAEDGTSIG VVGMDIDFGT LTDLTDAISM YDTGYAFLIN AQGVVMHHKE
LENGTSMGEQ DSSLSDIVTF LSDDTNEGKG HLYTYQGVRK QMYYFNLDNG MKLVLTAPNG
EVYAEANQLV GMTLIGLVIA LLICSVLGIV VGNNIAKPVK YVTEIIEQTS RLDFSPTEMG
SRLRRQKDEI GVMARAVHEM RKILRDIMAR LDEANRTITG GVDRLDEIMK VNSDLAQDNS
AATQELAAGM QETLANTQHI VQNIAEVKQN SESIYQMALN GVEQSHQAYE RAAAMEKTST
QSSKQANEIY EQMKDKADAA VEQSKAVQKI NDLTNEIKEI SSQTNLLALN ANIEAARAGE
AGRGFAVVAS EIGSLASQTL STVGNINSIV VEVNDAVSSL TQCITTIMDF LENTVVNDYA
QFQKSGTEYR TDSDDFKNIM GQTKDSMQLL EKYIDEISTA SDGINDMMSQ STSGISDIAE
KSSQTQTSTA EGYNRLQECR ESIEQLKKIV EQFHLG
//
