ID R7R6I8_9FIRM Unreviewed; 417 AA.
AC R7R6I8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Capsule synthesis protein CapA domain-containing protein {ECO:0000259|SMART:SM00854};
GN ORFNames=BN450_02717 {ECO:0000313|EMBL:CDF46319.1};
OS Roseburia sp. CAG:100.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262940 {ECO:0000313|EMBL:CDF46319.1, ECO:0000313|Proteomes:UP000018092};
RN [1] {ECO:0000313|EMBL:CDF46319.1, ECO:0000313|Proteomes:UP000018092}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:100 {ECO:0000313|Proteomes:UP000018092};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CapA family.
CC {ECO:0000256|ARBA:ARBA00005662}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF46319.1}.
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DR EMBL; CBKV010000265; CDF46319.1; -; Genomic_DNA.
DR AlphaFoldDB; R7R6I8; -.
DR Proteomes; UP000018092; Unassembled WGS sequence.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd07381; MPP_CapA; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR019079; Capsule_synth_CapA.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR33393:SF12; LIPOPROTEIN-RELATED; 1.
DR PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR Pfam; PF09587; PGA_cap; 1.
DR SMART; SM00854; PGA_cap; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Reference proteome {ECO:0000313|Proteomes:UP000018092};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..417
FT /note="Capsule synthesis protein CapA domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004443403"
FT DOMAIN 76..324
FT /note="Capsule synthesis protein CapA"
FT /evidence="ECO:0000259|SMART:SM00854"
FT REGION 45..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 417 AA; 46357 MW; 9EEB0ED2D0C25DEA CRC64;
MWKDKGIKII ILMLAALLNV GCGSHEAVAA STMNQSTEAV TTLESTEQLP MSQQPEQTLE
ESSTEAYVEE EKQKVDLVMV GDVLLHEKVA QSGQMPDETW QYDHLFAQVR DEIEAADLAL
VNQEVILGGR ELGLSGYPSF NGAYEVGDSL VNAGFDVVLH ATNHVLDKGR KGLLNCIHFW
KEKYPQIAVL GIHETKEEAD TVYVTEVNGI RIAILNYTYG TNGISLPKDM PYAVDIWNED
KIRTDMQKAK EAADFIVVCP HWGTEYKLQE SKDQQQKAQF LADQGADLII GTHPHVIEPV
TWIQSASGKE VLVYYSLGNF INATSGTGQG TAARMVGAMA QVTIEMDEQN RPYISSYGVE
PLVTHNVSGT GQITTYRLKD YTEELAVQNE MRKQDPSFSL SYCQSICREV FGDLYQQ
//
