ID R7RQX5_9CLOT Unreviewed; 438 AA.
AC R7RQX5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=UDP-glucose dehydrogenase {ECO:0000313|EMBL:CDF57751.1};
DE EC=1.1.1.22 {ECO:0000313|EMBL:CDF57751.1};
GN ORFNames=TCEL_01665 {ECO:0000313|EMBL:CDF57751.1};
OS Thermobrachium celere DSM 8682.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Thermobrachium.
OX NCBI_TaxID=941824 {ECO:0000313|EMBL:CDF57751.1, ECO:0000313|Proteomes:UP000014923};
RN [1] {ECO:0000313|EMBL:CDF57751.1, ECO:0000313|Proteomes:UP000014923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8682 {ECO:0000313|EMBL:CDF57751.1,
RC ECO:0000313|Proteomes:UP000014923};
RA Ciranna A., Larjo A., Kivisto A., Santala V., Roos C., Karp M.;
RT "Draft genome sequence of the hydrogen-ethanol-producing anaerobic
RT alkalithermophilic Caloramator celere.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF57751.1}.
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DR EMBL; CAVN010000090; CDF57751.1; -; Genomic_DNA.
DR RefSeq; WP_018661187.1; NZ_HF952018.1.
DR AlphaFoldDB; R7RQX5; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_2_9; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000014923; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0003979; F:UDP-glucose 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CDF57751.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014923}.
FT DOMAIN 328..423
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 438 AA; 48843 MW; C1CA54A320E1348D CRC64;
MVKEQYKNVA VFGQGFVGLP LALSFAMRGC NVYGVDVVEP LVNDINNGIT HHTEEFEGKG
IREILREQLD AGRYRATTDM EEALKKCNNI VVTVGIPIRN GEHDLSDLLG CVTVIGKNLK
KGDLVVIRST VIPGTTEEKL LPILEKESGM KAGVDFYLAY SSERIAEGKA FYEFAYMPTV
VAGINEESAV RAKELLEVVC KADVIVASDM KIVETSKVFE NVQRDVNIAM VQEFARFTEA
LGIDIYEVIK VANTHKRVNL LTPGPGVGGY CIPNAYHYLE PKARELNVDL DLLKLARLKN
SNLPNIMVNM LESMLLKEGK TLEGSKIGVL GLAMKDYSND DRISPPIEIV KILQRRGALV
FAYDSAVPTE YDFKVCDIID ALKDKDAIMI LAKQKDYDNF DDKYLEVISR GTVILDTRNL
FEGKEEKLKE YGIKLMKI
//
