ID R7RR55_9CLOT Unreviewed; 609 AA.
AC R7RR55;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase {ECO:0000313|EMBL:CDF57745.1};
DE EC=4.2.1.- {ECO:0000313|EMBL:CDF57745.1};
GN ORFNames=TCEL_01659 {ECO:0000313|EMBL:CDF57745.1};
OS Thermobrachium celere DSM 8682.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Thermobrachium.
OX NCBI_TaxID=941824 {ECO:0000313|EMBL:CDF57745.1, ECO:0000313|Proteomes:UP000014923};
RN [1] {ECO:0000313|EMBL:CDF57745.1, ECO:0000313|Proteomes:UP000014923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8682 {ECO:0000313|EMBL:CDF57745.1,
RC ECO:0000313|Proteomes:UP000014923};
RA Ciranna A., Larjo A., Kivisto A., Santala V., Roos C., Karp M.;
RT "Draft genome sequence of the hydrogen-ethanol-producing anaerobic
RT alkalithermophilic Caloramator celere.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF57745.1}.
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DR EMBL; CAVN010000090; CDF57745.1; -; Genomic_DNA.
DR RefSeq; WP_018661176.1; NZ_HF952018.1.
DR AlphaFoldDB; R7RR55; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_9; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000014923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:CDF57745.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014923};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 283..566
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 609 AA; 68579 MW; 881CE61E5BFF7DE9 CRC64;
MNKKIEQILY ALLDIIFIHA SIFAGYFARF SWNIPTEYLK IYRLSAIPIT FIMIFSFYVF
KLYKSIWRYA SINELISVIL AVTSGAIFSY VYGEIIGYRL PLSVYFIMWA LTILASGGIR
FLRRLISSIE MLPKDVLKKS ARVLVYGAGD AGALVVKEMR KHPELGYIPV GFIDDDKNKW
GKSINGINIL GGREDLDSIV INKDIDEIII AIPSLNNEDR KEILEVCSKT GCKLKILPGV
YELIEGKISI NQIRDVEIED LLGREPVELN IEEIAGYLKN KTVLVTGGGG SIGSELCRQI
VKFNPKKLLI LDINENGAYE LQTELQFKYG KNIDLDVIIA SIREKNRLEE IFNKYKIDVV
FHAAAHKHVP LMEANPKEAI KNNIIGTMNL AEVSSKYNVN KFVLISTDKA VNPTNIMGAT
KRFCEMIIQA MDKVSKTEFV AVRFGNVLGS NGSVIPLFKK QIKEGGPITV THPEINRYFM
TIPEAAQLVI QAGAMAKGGE IFILDMGEPV KIVDLAKNLI RLSGLEPEKD IKIVFTGLRP
GEKLYEELLM DEEGLQKTAH KKIFVGKPGN YDINDIKTKI EILKENLSAD DETLFTIMEE
YVPTYKRNK
//
