ID R7RX59_STEHR Unreviewed; 552 AA.
AC R7RX59;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=G-alpha-domain-containing protein {ECO:0000313|EMBL:EIM79929.1};
GN ORFNames=STEHIDRAFT_105968 {ECO:0000313|EMBL:EIM79929.1};
OS Stereum hirsutum (strain FP-91666) (White-rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Russulales; Stereaceae; Stereum.
OX NCBI_TaxID=721885 {ECO:0000313|EMBL:EIM79929.1, ECO:0000313|Proteomes:UP000053927};
RN [1] {ECO:0000313|Proteomes:UP000053927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FP-91666 {ECO:0000313|Proteomes:UP000053927};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; JH687400; EIM79929.1; -; Genomic_DNA.
DR RefSeq; XP_007310919.1; XM_007310857.1.
DR AlphaFoldDB; R7RX59; -.
DR GeneID; 18794776; -.
DR KEGG; shs:STEHIDRAFT_105968; -.
DR eggNOG; KOG0082; Eukaryota.
DR OMA; FQLAYAY; -.
DR OrthoDB; 1864818at2759; -.
DR Proteomes; UP000053927; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053927};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 552 AA; 62852 MW; 6FF21B4A3E4497B9 CRC64;
MPRHSRTSLD YDPLTAAIAP PSDETPEQRA KREQDEAEAQ RVSDLIDEQL KAERAALKKK
KPPIKVLLLG QSESGKSTTV KNFQLAYAHN AWLEERASWR SVILLNLVRS VNTILDILGK
EMHYVSSPPP SSNLRLPPTS PTSSQTSDED DDDEEDEPER NLPAPLPRRP GSASPPATQQ
DIALYQMQMR TRNTRFLFTE KHRLLQMRLK PLRRVQRDLE QLLGAPSFVE ADDLRGPATP
FASMEGSSPS STVSSRKRMS QSHEFVVRSR NGWKGALRLG GDEDERERGE RGKGGKRGRD
ERSEETMGVI SGCGEDIRAL WADPIVQEVL AKRGVKMEDQ PGFFLDEVDR IATRDYEPSD
DDVVKARLRT TGVQEYHFLF EKGSEAGREW IMYDVGGARS YRSAWYPYFM DVNAIIFLAP
ISVFDEPLAE DRKVNRLEDS FLLWKAVCSS RLLSKVQLIL FLNKCDLLQR KLKRGSQLRQ
YIPTYGDRPN DLANVAKYFR QQFREMSRRY SPEQRSFYSF LTSVVDVKST AVTLGTVREG
ILRNHLANAE LI
//
