ID R7T1F1_DICSQ Unreviewed; 654 AA.
AC R7T1F1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Cysteine proteinase {ECO:0000313|EMBL:EJF62254.1};
GN ORFNames=DICSQDRAFT_146528 {ECO:0000313|EMBL:EJF62254.1};
OS Dichomitus squalens (strain LYAD-421) (Western red white-rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Dichomitus.
OX NCBI_TaxID=732165 {ECO:0000313|EMBL:EJF62254.1, ECO:0000313|Proteomes:UP000053319};
RN [1] {ECO:0000313|EMBL:EJF62254.1, ECO:0000313|Proteomes:UP000053319}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LYAD-421 SS1 {ECO:0000313|EMBL:EJF62254.1,
RC ECO:0000313|Proteomes:UP000053319};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
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DR EMBL; JH719406; EJF62254.1; -; Genomic_DNA.
DR RefSeq; XP_007364966.1; XM_007364904.1.
DR AlphaFoldDB; R7T1F1; -.
DR GeneID; 18836593; -.
DR KEGG; dsq:DICSQDRAFT_146528; -.
DR HOGENOM; CLU_013485_1_0_1; -.
DR OMA; HHTFDNI; -.
DR OrthoDB; 1749511at2759; -.
DR Proteomes; UP000053319; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR CDD; cd02662; Peptidase_C19F; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF945; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 11; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053319}.
FT DOMAIN 1..445
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 200..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..326
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..561
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 71775 MW; 2917A93E37ED1FA3 CRC64;
MASLSYLQPQ LEKIHARAEA LDVPTPVIDT LRDLVYALNN PSSHPRAIRP FDIINALSHH
NSGKHNSLFS SREHQDAQEL FQLLSECIKS EATAVAKEIR RDRGLGELTQ KDDRASRDLS
QTVFDGLTAN RRSCVECGYT EAVMHFPFDN WQLAVPRLVA ACRLEDCLDD YTRLELLDDC
ICRKCSMLAT YKRLEEEANR TTEAAAAIND PTSSKKKRAR DSRKLLARVK AALDEGRIEE
DIKGVKMEKV CSRASTKQSM IARPPPVLAL HLNRSMHYGG YAAKNNCRVV FPEILDLTPY
TTSGQLSTQP SAPISSPPPP IPIQRSVTPT PSTYAVPRTL YRLSAVVCHY GQHSFGHYVC
FRRKPRPPAA GDRRYTPPRL QCAIGCDCNL CVQQGPIREE DGQNPSRPGT GRGWLRISDD
TVQECGIERV LQEGAGAFML YYERVQQPRS VVYNNAPPRA SEETIRPEES HAPTPEVASE
KPAEKEHALN GEAARKHEGR DRERPEERER SVVDPRVVRR VSASAHLKAS ASPSTQPQSP
SQAQAPPPKP PSKPAAVAPP PPISRSTSGS SAVTAVSTFS TKTLASDASA PNGHAHSSHP
RDKHGSNGSA DPSSPQRPSM PPSSPSKLRK SRRSVSQADG NPTSSPTTST PLRT
//
