ID R7T9A8_CAPTE Unreviewed; 1445 AA.
AC R7T9A8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
GN ORFNames=CAPTEDRAFT_225496 {ECO:0000313|EMBL:ELT90028.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT90028.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT90028.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT90028.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP225496}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AMQN01003148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB311062; ELT90028.1; -; Genomic_DNA.
DR STRING; 283909.R7T9A8; -.
DR EnsemblMetazoa; CapteT225496; CapteP225496; CapteG225496.
DR HOGENOM; CLU_004165_1_0_1; -.
DR OMA; NVHCLKT; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR CDD; cd17737; BRCT_TopBP1_rpt1; 1.
DR CDD; cd17731; BRCT_TopBP1_rpt2_like; 1.
DR CDD; cd17718; BRCT_TopBP1_rpt3; 1.
DR CDD; cd17749; BRCT_TopBP1_rpt4; 1.
DR CDD; cd17727; BRCT_TopBP1_rpt6; 1.
DR CDD; cd17728; BRCT_TopBP1_rpt8; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 9.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR049542; TopBP1-like_BRCT0.
DR InterPro; IPR044737; TopBP1_BRCT_1.
DR PANTHER; PTHR13561; DNA REPLICATION REGULATOR DPB11-RELATED; 1.
DR PANTHER; PTHR13561:SF20; DNA TOPOISOMERASE 2-BINDING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 3.
DR Pfam; PF12738; PTCB-BRCT; 2.
DR Pfam; PF21298; TopBP1_BRCT0; 1.
DR SMART; SM00292; BRCT; 7.
DR SUPFAM; SSF52113; BRCT domain; 6.
DR PROSITE; PS50172; BRCT; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 131..202
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 228..313
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 381..471
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 580..666
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 703..749
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 903..994
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 805..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1082..1144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1422..1445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1445 AA; 160542 MW; 55D8B72B370B8724 CRC64;
MVQGQESDEI QCCLWFTRKL QLTKVVTVIM NSSVSSPSLV CRFVKAGDTP SSVCSEAFEE
IRSLGPTSEW LSTSDALKVE GKDRRFLYVF EEFSGAAFEH IASTGNRIYG PICVLHCMKN
EQPLPRLSHP VYSLAMKGIT VSCTGLPKAT RETLHHRVQW MCGEVSKDFH EGVTHLVAGE
VGSKKYLVAA NLGKSIMAPE WLDAVYESSK ASFTHASEAE FNQWKCPLLR GYVITVSGLN
SSDRQKIKET IEREGGRYTG EMKINECTHL IINEAKGQKY EFAKKWRIHI VRPDWLNTCI
EAGYAVEEYK YKVTEGNPGQ GATISTPNSS RNLSNVSNLS NLSAISMTHI NETANTTMQT
TFNQTRSVDP LDLLVQNMPS RGDMFLDGCK IFLSGFNANQ LEKLRRIINH GGGTRFNQIN
GSVSHVIIGD RVDEDLEQIE RSGLRPHVVT VDWLVDCLNQ GRCMPEESYH CLDATMDTTE
QSYLKTPKAG RINNNSFAQA PKTVVASSSD DMADIMSQYL PNNSQAGGSL GESTLLRAAM
GTPSQDRTLV EPETLRKDKT YDEDMTQDLS GGGDMTSESQ NVKIFAKKTF VIVGFDGSSR
PELEEFIQEA GGKVLPENTR RSIPDYALVP LFSVPVEMTV GEVVTNAWLQ MCVQDGIIYP
TESNPVFLPM DVDQDARPLE GCVLSISCQE FFVKKAQKNL KGSTHLITAL ADGSKYTAAK
KWKLPALHKE WLIDSLKSGR RLPEVDYDVD IPLNTGENDE SATFEEIPHF SVPAPIVRAE
DKAEVKEMIT TPLMNTRVME LRHGVTTPHQ PAASTNGTPG ESPFSVRPRI NLGSFLDSPP
TPQTPGGTKK SRLSEASELG ELMHQQLTKR LAAYEDKPEE KPDQRRFSLQ SQPMMVDVDS
PAVTLKALHG VVVVVAKKLS KQQRELNALA VGLGAEYIWT YNSKCTHYIF QGRQNDLNKE
FRMARDDGKT IVSPHWLNVC AEQNCRVDES LFPHTFNPSM SLSVSSTPAL STRRSARTRA
VCSKGETEAP APIADLFNSK MDQDVLNATQ SDEEMALACG DAEEEQKENK TDLYVKQLQN
LMEVTKTTRS KRRTRKTESP DTNSSSEMIR NLSRNSLRDS IDPERSKNKS HPFMETASEP
SQMYEVSWDD PGVRKQQEIL APELLKNSES FSPKMHIEGD KDSDNEITFK APEVTNVSIV
EEPPSPAEEE PEIIKRHFLF SGFPQKDKAN YTALIERLGG IATDAGCYES TCTHLVVGTS
CSSVHLTLLK SSEFQLNPRG ETEHEWGGEC TQELIKTLPP NMGKLARAAH RWRKSLSQEN
NSGAFQSWKV MLMTDKKKEN GFKRLLEAGG ALVCPADVDI SSITHLFIEP AKIETKVDLQ
KFVDAGIHCV KPEYIAAFLT ENVSPKPAVY YVPEALALVN SKDKKRKASG GNTENAATPK
KRPKT
//
