ID R7TB59_CAPTE Unreviewed; 505 AA.
AC R7TB59;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 13-SEP-2023, entry version 37.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_154442 {ECO:0000313|EMBL:ELT90968.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT90968.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT90968.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT90968.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP154442}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the unc-93 family.
CC {ECO:0000256|ARBA:ARBA00009172}.
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DR EMBL; AMQN01003004; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB310691; ELT90968.1; -; Genomic_DNA.
DR AlphaFoldDB; R7TB59; -.
DR EnsemblMetazoa; CapteT154442; CapteP154442; CapteG154442.
DR HOGENOM; CLU_025356_1_1_1; -.
DR OMA; NTLICIT; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR19444:SF13; PROTEIN UNC-93 HOMOLOG A; 1.
DR PANTHER; PTHR19444; UNC-93 RELATED; 1.
DR Pfam; PF05978; UNC-93; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 64..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 505 AA; 56420 MW; 7740AC7E713D0736 CRC64;
MRNQQQQNMH ISPIPEGVSL SSLDSLPSRQ QSETHPGGGV ATIEMSSEEL AAYRHSRWRY
GKNLVVLTLS FILVFTAFRS IQNLQSSLNS AGRLGMVAMA CVHGTTFLTC LFAPALIDRL
TSKWTIVLGL LFYLFWVAAN FYPHVYTLVP TSIGVGFGQS LAWGAQVTYI QKLAVDYAHA
SRELTQQEMY KFNGVFLACF QTSHVWGNLV SSLMLTENST KSDCGIYDRC SEEVHRVWNI
SSGLETADDT VLKLMGSYLV FAFTGFALIL ICLERIGTKA DPEKPCLQPR SLQMVWRNVQ
QLVKHKTYRL LIPLLIFNGF EQGFVYADYN KSYITCSIGI HYVGYNMITL GMTNSLFSVL
IGMVSKHLPR EAIVGMGAIL HIGLMVFLLV WIPDVKLVPV FFAVSALWGI CDAIWQTQCN
CLVNLSCPDD HDVAFQNFRM LQGLGASMAF GMGAFTCVSA KLYFLITLLS LAVLLYAAVE
YQLRKAEEEE EYAAQNHGRN LEEPT
//
