ID R7TG61_CAPTE Unreviewed; 986 AA.
AC R7TG61;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=MI domain-containing protein {ECO:0000259|PROSITE:PS51366};
GN ORFNames=CAPTEDRAFT_167187 {ECO:0000313|EMBL:ELT90541.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT90541.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT90541.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT90541.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP167187}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC -!- SIMILARITY: Belongs to the CWC22 family.
CC {ECO:0000256|ARBA:ARBA00006856}.
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DR EMBL; AMQN01014286; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB310862; ELT90541.1; -; Genomic_DNA.
DR AlphaFoldDB; R7TG61; -.
DR STRING; 283909.R7TG61; -.
DR EnsemblMetazoa; CapteT167187; CapteP167187; CapteG167187.
DR HOGENOM; CLU_006308_1_0_1; -.
DR OMA; MINQRIV; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR18034; CELL CYCLE CONTROL PROTEIN CWF22-RELATED; 1.
DR PANTHER; PTHR18034:SF3; PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51366; MI; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 484..600
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 1..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 679..986
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..466
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..749
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..839
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..855
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 867..976
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 986 AA; 113533 MW; 1D56DF312F40FEDC CRC64;
MSDSEIRRGS FESESESESE DDALKPSLRS HVVSQADSVN NKRKRRESES PVRNGHSDDG
GSDGERVQRR NWRENERGRD DRGTFPRFRD HRRDDRRYSS HRYSDRGRDG SRRDDHRDER
KRKAEGDEGV DENADPKLEA EKLAKRAKKN DDVNTRTGGA YIPPARLRQM QAEITDKGSQ
PYQRIAWEAL KKSLNGLINK VNVSNIKDIV HELFQENIVR GRGVLVRSIM QAQSASPTFT
HVYAALVSII NTRFPQIGEL LLKRLVIQFR KGFRRNNKDL CLSSVKFVAH LVNQQVAHEI
IALEILTLLL ETPSDDSVEV AVGFMKEVGL KMGEVSPRGM HAIFERMRTV LHEGEIDKRV
QYMVEVMFAV RKDGFKDHPA VLPELDLVDE DDQFTHMLTL EDAVDPEDML NIFKFDPDYE
AVEEKYKTLK REILEADSSS DEDGSGSGSG SSDSDDEEEG EGEGEEAAAG DSNIIDATET
NLVALRRVIY LTIQSSLDFE ECVHKMLKID LKPGQEVELC NMILDCCAQQ RTYEKFFGLM
AQRFCMLDKK YVEPYQKIFI EQYESIHRLE ANKLRNVSKF FAHLLFTDAI SWEVMESIKL
NEDDTTSSSR IFIKILFQEL SEYMGLPKLN DRLKDETLQT HFEGLLPRDN PRNTRFAINF
FTSIGLGGLT DDLREHLRTM PKPAPVPQPE EEESSSSSSS SSSSSSSSSS SDSSSDSSDS
DSSSSSSSSS SSSSSSSSSS SSSSSSSEEE EEQPAPKRES PRGRHEQVAE RERSRQHESG
GDSRQRVREE RRSRERPRAE RSGREQHQAE KDAINESLQK RQRERGSRAR DEELMREIQK
ESGSSSSSAD SSSDSSSSDD SEEEQTKEGE QERRRPAREE EEDRRRRPAR EEEEDRRRRP
AREEEEDRRR RPAREEEEDR RRRPAREERQ SEERQDSRRR RRASSSGDER QGRSQYEERD
RRNRDRQQQL RRSRSRSGDR RRDRRR
//
