ID R7TKG8_CAPTE Unreviewed; 456 AA.
AC R7TKG8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Delta-like protein {ECO:0000256|RuleBase:RU280815};
GN ORFNames=CAPTEDRAFT_188763 {ECO:0000313|EMBL:ELT91610.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT91610.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT91610.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT91610.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP188763}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: Putative Notch ligand involved in the mediation of Notch
CC signaling. {ECO:0000256|RuleBase:RU280815}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280815}; Single-
CC pass type I membrane protein {ECO:0000256|RuleBase:RU280815}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00377}.
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DR EMBL; AMQN01013707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB310412; ELT91610.1; -; Genomic_DNA.
DR AlphaFoldDB; R7TKG8; -.
DR STRING; 283909.R7TKG8; -.
DR EnsemblMetazoa; CapteT188763; CapteP188763; CapteG188763.
DR HOGENOM; CLU_600276_0_0_1; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 2.10.25.140; -; 1.
DR InterPro; IPR001774; DSL.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF8; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF01414; DSL; 1.
DR SMART; SM00051; DSL; 1.
DR PROSITE; PS51051; DSL; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|RuleBase:RU280815};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00377}; EGF-like domain {ECO:0000256|RuleBase:RU280815};
KW Membrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU280815};
KW Signal {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280815,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..456
FT /note="Delta-like protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008787105"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 96..142
FT /note="DSL"
FT /evidence="ECO:0000259|PROSITE:PS51051"
FT REGION 419..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 98..107
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 133..142
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
SQ SEQUENCE 456 AA; 50118 MW; B68871DF39DB6D3A CRC64;
MVCAGVRILW LLLLAASPAQ EYITFGDKIG ETPNPMVFEF NKWTGGVKIH IDVYDKDSNN
DDYVDGISTI HRGLPGQFEN LLTAEARTSL RLGVQVICDL NYYGDDCTHY CHGHDSDAEG
HYTCADQTGA MLCIPGWTGP DCKTNKTAHI ITTQAMTSRI TTVTTNPTDP TTTNTEPTTR
ITEPTTSVAT TRTIILSSLT TTASDSSTEV TDTRNVTEEQ LHDREIACEV GFYGIKCREK
CGHCKNDSCS YVDGHCLDGC QLWFIGDLCK EEIALPSLAG SNAFLRRVND SAVAITWTQD
PQIPDKHAAY YSYTVAYTEG PGNFNNGPSI THDPAVTKQT LIVANIQSDN DYYFEVQIYR
EMSGEKEYGW PSGTTHTESS SIPVNVFVAN WEFFIVGFCV LLIIILSVIV IVQRFKPQKG
DSEKNHDNIA LEDSAAQAPT VPDKTACQPS PATESP
//
