ID R7TQ94_CAPTE Unreviewed; 569 AA.
AC R7TQ94;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Vacuolar fusion protein MON1 homolog {ECO:0000256|RuleBase:RU367048};
GN ORFNames=CAPTEDRAFT_164017 {ECO:0000313|EMBL:ELT95737.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT95737.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT95737.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT95737.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP164017}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: Plays an important role in membrane trafficking through the
CC secretory apparatus. {ECO:0000256|RuleBase:RU367048}.
CC -!- SIMILARITY: Belongs to the MON1/SAND family.
CC {ECO:0000256|ARBA:ARBA00008968, ECO:0000256|RuleBase:RU367048}.
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DR EMBL; AMQN01011686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB309028; ELT95737.1; -; Genomic_DNA.
DR AlphaFoldDB; R7TQ94; -.
DR STRING; 283909.R7TQ94; -.
DR EnsemblMetazoa; CapteT164017; CapteP164017; CapteG164017.
DR HOGENOM; CLU_014574_3_1_1; -.
DR OMA; SHLGQHM; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0006623; P:protein targeting to vacuole; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR043972; FUZ/MON1/HPS1_longin_1.
DR InterPro; IPR043971; FUZ/MON1/HPS1_longin_2.
DR InterPro; IPR043970; FUZ/MON1/HPS1_longin_3.
DR InterPro; IPR004353; Mon1.
DR PANTHER; PTHR13027; SAND PROTEIN-RELATED; 1.
DR PANTHER; PTHR13027:SF7; VACUOLAR FUSION PROTEIN MON1 HOMOLOG; 1.
DR Pfam; PF19036; Fuz_longin_1; 1.
DR Pfam; PF19037; Fuz_longin_2; 1.
DR Pfam; PF19038; Fuz_longin_3; 1.
DR PRINTS; PR01546; YEAST73DUF.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 169..291
FT /note="FUZ/MON1/HPS1 first Longin"
FT /evidence="ECO:0000259|Pfam:PF19036"
FT DOMAIN 330..427
FT /note="FUZ/MON1/HPS1 second Longin"
FT /evidence="ECO:0000259|Pfam:PF19037"
FT DOMAIN 458..558
FT /note="FUZ/MON1/HPS1 third Longin"
FT /evidence="ECO:0000259|Pfam:PF19038"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 45..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 64082 MW; EF70C98D56FAC59B CRC64;
MAAEISNDSP SDEILQGSEP GASRNSMLLA TDSYDDLASY LSDTNLSSDR DRLSSGSISE
ITHPTETESF DPKSVISEEV GPEVVENEIN EQLENSLDVS ASPVDEPAAL ATSDSDTVTE
RIGLDTPTSQ LSELSTDHSQ PEACTGNNSD EQEEEVEYVH SQEWRQHRKH VFILSQSGKP
IYSRHGDEDR LVTLMGVMQA LVSVIGDGQD LLRCITAGSH KMVFLIRENL VLVAAARSIE
SMPQLLLQLT YVYNQVLSVL TLSQLSRIFK QRRNYDLRRL LTGAEKFFDN LLNTMDRDPC
FFLGAVRCLP LESSMRDTIA QSIAQNAKVK DLVFAILIAD NQLITLVRMK KYFLHPLDLH
LIFNLVSASE SFKAAESWTP ICLPKFDSGG YLHAHISYMD EECRSCLLLL TVDRDVFFTL
SECKEKIRER LVKYKCLAAI AESVDQNGYK TSQVGIPELR HFLYKSRSAA QFSCPEYEAP
YHTADQRDRL FGLYQFLHHR IHSSSRPLKI LFHVGSHETL LGWVTSGFEL YAVFGPLVTK
SAAINSVNKL LKWIKKEEDR FFILNSPTF
//
