ID R7TXC8_CAPTE Unreviewed; 609 AA.
AC R7TXC8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Rap-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_146981 {ECO:0000313|EMBL:ELT98588.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT98588.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT98588.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT98588.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP146981}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01010418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB307754; ELT98588.1; -; Genomic_DNA.
DR AlphaFoldDB; R7TXC8; -.
DR STRING; 283909.R7TXC8; -.
DR EnsemblMetazoa; CapteT146981; CapteP146981; CapteG146981.
DR HOGENOM; CLU_002127_1_0_1; -.
DR OMA; LEIECIL; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF70; RAP-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 141..358
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT DOMAIN 505..569
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 609 AA; 68184 MW; 31BE3F4B54304EE1 CRC64;
MYYRNFFHGY GKFLSTQFVL PQCSLLSVVD HQNFVGIDEK LGPVAISFRR EKVDDKERET
TTGKMEGGGA CHQYRLIVRT GELECLRGSV IEEAIPSSSR LSNTRGLPPK DVLEFLFPDE
INLSSLKVAS ASNAASIGEQ LLKLDEQRVS LTYKVGVLLC RAGQQTEEEM YNNEHGSPAF
DEFLDCIGER VPLKGFEKYR GGLDCKTDST GTHSLYKQID DYEIMFHVST MLPFTPNNRQ
QLLRKRHIGN DIVTIVFQEP GSLPFTPKSV RSHFQHIFII VKAHHPKTEH VKYSLAVTRS
KDVPPFGPLF SEGAMFSKSL EFARFLAIKV INGENAVHCS EKFLAMARRT RQEYMKELVN
TNAGTTSLDS ASKLSKFSLG SGRRKERPKV RTVPDVFATG AVSWSVQVTA HSSPWTEDFG
TSSQLDAHLG IGSTLLVLID VATKRVLSSI ACKLIIGWTA NGRSLRIYYN NNECIMIRMP
PSEVDEIREV VTRLSLVTRG AQTEEFTLRR NSLGQLGFHV HFEGIISEIE QHGFAWNVGL
RNGARLVEIC KVATCTLTHD QMIDLLRTSV TVKVVVIPPY EDGAPRRFVV TPLVLYISSL
CANTSIKRL
//
