ID R7U0Z6_CAPTE Unreviewed; 2952 AA.
AC R7U0Z6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=DNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_224509 {ECO:0000313|EMBL:ELT96855.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT96855.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT96855.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT96855.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP224509}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01000248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB308724; ELT96855.1; -; Genomic_DNA.
DR STRING; 283909.R7U0Z6; -.
DR EnsemblMetazoa; CapteT224509; CapteP224509; CapteG224509.
DR HOGENOM; CLU_000315_5_2_1; -.
DR OMA; PGTACQF; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18668; CD1_tandem_CHD5-9_like; 1.
DR CDD; cd18663; CD2_tandem_CHD5-9_like; 1.
DR CDD; cd17995; DEXHc_CHD6_7_8_9; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 3.40.5.120; -; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR006576; BRK_domain.
DR InterPro; IPR037259; BRK_sf.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR46850:SF2; -; 1.
DR PANTHER; PTHR46850; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9; 1.
DR Pfam; PF07533; BRK; 2.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00592; BRK; 2.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF160481; BRK domain-like; 2.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 928..977
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 1029..1203
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1343..1494
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1594..1658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1890..1953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2191..2295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2350..2370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2447..2468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2557..2582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2640..2670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2741..2781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2833..2925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2933..2952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 648..663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..684
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1607..1624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1907..1929
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1939..1953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2207..2230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2256..2290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2354..2370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2568..2582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2641..2670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2849..2863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2880..2912
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2952 AA; 330778 MW; 613C7614F55CD18E CRC64;
MEDQSMLGMF ESDTTSFLEE LAGPANSMPV GGGMMPQQPQ QPPQPQPGGI DPAMSSLQHM
QQPQGWGQPP QQKLHHYSDF NQPRQVGPGQ PQPGMMSPHQ FTNAPASQIS PGYNFQSSHS
PRVTSPQHSA WPPQQQPPST QNSNMQQYGP MKGNYHEYPM SANSSQPGPG GHHPHPGHYP
QQAQGNRYPN PMVSPPPNMA MGMNHGGQYS MQGPNVMPMQ QQPPGYQAMH RDQMNGNRMY
GGTYNQPGGM MPPGAMAKQM GHYPQHPQQQ SYPGFNPSSQ GNFAPPSQQS HIMQQQQRPP
VSSAWMPDAS AAPHQQQQQQ QQPPPMDKQA NVQLTTAQGN PQQLAAEIHQ LQQQVTQLYG
MPQAPQTQQK MLDVQERLRT LKAQQLMQQQ QQQQPGGYPQ DQQPQPIQAG PGTGINVQQI
QTQPGQMQQT IIIHQQPQAQ SKLIVQQHQP ASMAEGSNMS TPTTQSSTVL ILPTTITTTP
SMLPSQQQAP VNSKASADDF PPLQLQDGMD QGAPMKDVRA DELNTPTTSP LNMQDADGEN
QNQEKANKII QEAIAKAQAQ GRPVPGIVNP GVPAVAPVME MEDEEKKKKA AKKERKKKEP
KPKKPKKEKD EKKRATPKKK KKKDEDDGDE MVDAAAAAAD DVEMPADAAA PAEEKEEKPK
KMVFKSKAKK KRTIPTFLKN KKRKRKHSSD DEMRMPMGSP PPSPSEEESG IQKRRSGRHM
KRKKYLDDFD LDLSEDEAKK AHHGSDLMFA DGSAENSLMT VDSQDSLVTK PVAFFVHANR
VNSQENPADE DALIIDKILG VRMGKRKLVL QVPEPPPAET IKKEGEEGNV EVECNGEVKE
EVKEEVKEEE AAGVGGGESA EKEGEEIETE EFYVKYKNFS YLHCEWRTAD ELERGDRRIQ
GKIKRFKLKK EQSFVLQDED ELFNPAYVEV DRILDSSRTK DPVTSEETQH YLVKWRGLSY
EDSTWEVAAD VDRAKIVAYE KFSTPPDEEH REAVARPSAS RWKKMEESPH YKNGNQLREY
QLEGVSWLSF NWYNKQNCIL ADEMGLGKTI QSITFLHSMY DYGIKGPYLI IAPLSTIGNW
SREFEVWTDM NAIVYHGTTA SRNMIQEYEM YHKDSEGKRI PDCYKFNALI TTYEVIISDV
EELSEIEWRA VVIDEAHRLK NRNCKLLEGL RCFDLEFRVL LTGTPLQNNT DELFSLLNFL
EPKQFSSSEA WSQEFGSLTS DTQVDKLKAL LKPMMLRRLK QDVEKNLAAK EETIIEVELT
NIQKKYYRAI LERNFSFLSK GGTSSNIPNL MNTMMELRKC CNHPYLVTGA EEQILEEARL
GGHELTHERQ FLAMVQSSGK LVLVDKLLPK LKAGNHKVLI FSQMTRVLDI IEDYIIQKKY
LYERIDGHIR GDLRQEAIDR FSKTDSDRFV FLLCTRAGGL GINLTAADTV IIYDSDWNPQ
NDLQAQARCH RIGQVKAVKV YRLITRNTYE REMFDKASKK LGLDKAVLQS MGPADLNAAN
GQLSKNEIEN LLKKGAYGAL MEDDKAGDEF CEQNIDEILE RRTQVIQVES GEKGSTFSKA
SFNVTGSRSD IDLDDPNFWQ KWAKKADIDT EDKQDQDLIM DLPRQRKQTT RYGNQDVMEN
MSELDSSDSE YDFKGQKINK GKKRRGRRRG DDDSEGDETP LGYFTRSDCF KVEKNLLVYG
WGRWDDILLH GRFKRKLQRE DMQTVARAML LFSLNHYAGD ERIKQFILDL ISQEQGQEKD
YTNHLGLAAP VPRGRKGKKK EKTNSKHSAF DEEMAKLDFD FESVLTDEGY KKHLKRHANK
VLLRVRLLYY LKQEIIGSQA DKVFTDIPAS EVDLPEPCCD GDPPVFWWDK EADRSILIGT
FKHGYEKYNC MRQDPTLCFL NRCGPPDSRA LAAEQNDEDP IKEDDDLDME STPSRGRSRT
RKRRGLDEEE DDIDSDMPGT PSSMASNKSK PVEMTVSENG KMPFPLFSDM NTRLRRVITG
YQRNHKKEVL RQEANAKRLE RREKYEAVLK EREKLRLDAL QAKWTRREEA DFYRVVSTFG
VERNRKTGEF VWETFRSLSK LDRKYKDTLT EYFLAFYHMC LRVCRRFKTE QEAIPPNSLP
VEPITEERAS RCLARIELLN KIREVILWHP KLSERLRLCQ ASPELPEWWV AGEHDKELLI
GAAKHGLART DYHILYDPKL AFRELVKQRI QNSSSSPSTP RAHEMPDIVS TKTESVDLKD
SKELAHPPEL TRDGDLGPPA LNKDEDANGG PVNLVKGEER VKKEEEAEEE VPPSLSKEVS
IKKDEEAASL DEEQGYPSDF AAEMQGSDIM AQAWNHPAVQ WPKDRVIAQR LESVCLCIEK
GEWPARRHLI SESDSRSSTP VRKSNTPQLN DYSLVEAAGT ASEGLKMTFQ KRRKRRTKAE
IEADRVSRLR ELAGISDAES ESQLSEMGDH RDSPLARGLC LTAAEEDSGL SGAEHSSHDK
RKHRKSKVDK LLEAAEMAAA GLQRSAGLQP STSGLKASLE PETRVPLVQL SDGSRLTGED
APMYKDLAQW LDEHPGYTLD LSVMEGEVQH ELEQALVQRR GRKRKEPSSS SSSATSSGDF
NVAVVNRDTG KRISGSKAPP LRYLKEWLMQ NPAYDVDAKW AHVVQAKGDL PSDMMKKRVL
TGGATSSSSS SRSRRHGNSN NSSSSSLGSS ASVSSAAAAS LLASDYYSSS SLASLSAMAN
YQKMMAMSPY SGLSASAMTN PLYANLLASY GLIPGMTGFE GMEGGEAPTP EQPAPSKSSK
KGKEESSSSP RSKSPANASA AAMASSSLHP ALSYMYGYNP MLLNQLYAQS LAAANFSLPT
SMASSMGSFA GLMQPNGVES EEETKAAAAS ETTETGTSRP QDLSVKKSSH KKAAASYSKP
QDLSVKSSSS SSKSAPDNAQ PEDLSTKKKS ATILKTPKVK SKSKLDSIVA AISAKAEAKQ
QQQDGDDSPG KA
//
