ID R7U1F4_CAPTE Unreviewed; 350 AA.
AC R7U1F4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 13-SEP-2023, entry version 39.
DE RecName: Full=Platelet-derived growth factor (PDGF) family profile domain-containing protein {ECO:0000259|PROSITE:PS50278};
GN ORFNames=CAPTEDRAFT_153454 {ECO:0000313|EMBL:ELU00054.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU00054.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU00054.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU00054.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP153454}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|RuleBase:RU003818}.
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DR EMBL; AMQN01009791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB306242; ELU00054.1; -; Genomic_DNA.
DR AlphaFoldDB; R7U1F4; -.
DR STRING; 283909.R7U1F4; -.
DR EnsemblMetazoa; CapteT153454; CapteP153454; CapteG153454.
DR HOGENOM; CLU_068126_0_0_1; -.
DR OMA; PEECICV; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR023581; PD_growth_factor_CS.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR PANTHER; PTHR11633:SF1; LD28763P; 1.
DR PANTHER; PTHR11633; PLATELET-DERIVED GROWTH FACTOR; 1.
DR Pfam; PF00341; PDGF; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00249; PDGF_1; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..350
FT /note="Platelet-derived growth factor (PDGF) family profile
FT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008787603"
FT DOMAIN 99..200
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
FT REGION 53..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 324..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 38667 MW; D891C5E6FAB85D7C CRC64;
MHHLTVLLFC VCLQLNFAVR EATRQRVAIP SLMKEFAASM PTTKDFIKAM VKKAPSKEAP
PGPSLGNPGP DRPEEEGMRE MEQMLFEPGS DRPTATGAET IQSMVTPPAA GCQPKDVTVT
LPSDPDPSVL YYPSCVTAKR CGGCCMQDQH ECGPTRVSKI NNKVVKARYP YLGAPNFLFE
GLVDVELDNH LECSCQCKNK PHHCDIAKHV YEAATCSCRC RNEDQRENCV APQTWDNHKC
ACTCPALKYC QAHEYFSFST CRCETSRDVV SDALSVGTVV DQVCVSTRCR ANYVAMNIMG
QCQCKMVSQW GDLAMANANA RVTGLPLPTT PVPEVTTRRR RPGRRPRPSK
//
