ID R7U708_CAPTE Unreviewed; 1775 AA.
AC R7U708;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=BEACH domain-containing protein {ECO:0000259|PROSITE:PS50197};
GN ORFNames=CAPTEDRAFT_196137 {ECO:0000313|EMBL:ELT99451.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT99451.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT99451.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT99451.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP196137}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01001915; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB306824; ELT99451.1; -; Genomic_DNA.
DR STRING; 283909.R7U708; -.
DR EnsemblMetazoa; CapteT196137; CapteP196137; CapteG196137.
DR HOGENOM; CLU_001454_0_0_1; -.
DR OMA; AYEQFTP; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44662; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR PANTHER; PTHR44662:SF1; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 291..563
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 1491..1522
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1529..1559
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 893..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1267..1302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 910..926
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 927..944
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1775 AA; 199971 MW; 913360006147F24F CRC64;
MLMVGELMVS AWREFHAVMM QCRKAVEKVV VFVLCLVNLC RCPWVDVVCL NGGSTAVYLM
LVHEDWISCL HQRTPFPKDL SAYSSLGPLD INLILAPSNA DIASPWHRIS VQPIGKTPES
GRGLPTVFAD SSHSHSDRDT QVKYPQAFQI KSRVRETAID PASQSTPFRA SHQNLCQVLR
ILESESSFYI VKPFHQYTLW DLVVFSPSKL HGCYSKLLFV VHQLVHAFQH CHQNGVTVGE
LALHDIVIDE NLWIHMTPRN LRSMCHCLRP QLNPAVNRHP LLSIQDLVQK YQTLKVDDIS
QLVSQWVKNE ISNLEYLMVL NHLAGRRYGD PNHHPILPWV MDFTSRDSGL RDLSKSKYRL
NKGDRQLDLT YEFHDGDVVI DPMAFPHHIS DFLSDITYYV YRARQTPKQI LCKYVRSRWV
PHEYPSNLQR LQAWTPDECI PEFFLDPTIF TSIHDDLCDL ELPEWADSTE DLLQAHCAIL
EGPYVSAHLH QWIDITFGYK LTGSAAVNAK NVCLQMVNKH TDLLNHGVVQ IFNYPHPRRL
PVPSPDIPHP RPDISDELEY KDSIPPITLP MGHNFVEALE NVENLSKFSM KTFRCLPPEN
RSESFPFPLR SDLVAQDMRV LGCLVAELAI SPKLRVLGPL TNLEKRYNLA REVCLSSLKD
IPRPLSRLLS YLLLLDSDWS STESPYPSIS SEGLPPPSSA ILLQPLYQLN SFPAFMSKLY
DILHKTKEID AQIVHISNTE HSVVERIVKT KKLCKRKVGL WHSYLSKYAR SLNQEGMELA
LPFLKELFTQ PSTAAFAAWS LFHPLASALG PSSMQTLYMS LLTQLFDHEH TTPKYLKLYH
RSFILQLIVG LRLGPFLENF TTRFIKASAG YKDFNEEEFI ERQVRQESAR VQRMLGRKQA
PSADMIRQES LNAGEEEKRV LAEHSDGEEA EEEVFEEEAL SLSEDQDQAP EVGRDALSTG
EPSLSSLEEQ NGGLEEVDDE GGEDGIIDMH QLTSTAMIRS ETGEFNRTSS SSDYNISQVA
AESIKWLIHR LGPVLAAKHL SVNLLQMLAL CYAGEKQLVF LDKSVAGRLS ELTRRPVVGD
QQAQHVIECL SCVAILYGEH VILIQFFQFL REVVNISVHR LTFRMEGGLI SSLHLLLSVI
PFLSDSTLMD ILEESIFRDI LLPLLKMVSS HHVIFPGGSQ ARTVLCLKIL DLLYLISLRI
GFEMTRQHMT FVLQKFFAAF SRVHEKRDAT PEDAEADNAT EVPTVEEQVY YEMKIDCTTQ
DYFIESSQSS STANKTPQSN SLRHSSTART PEAADNQSEQ EVHNELLSTF TPELAHTAYV
MFCRLAGGIH MEQNLVNIEL IQRLRVQHEA SLSPAELQGA GLTYAAAEYR EYEMNITCVV
ALQNHFTAAS PTEDSSVVSG SFGRNVTVAG NKIVLQNAPP NGDSKTSDQI ISQRLKSIDA
TTDSDKLRNP EMRLNCQRHL KGNWLAYWEH EIGRPSSDRS FNFKQIKLQS FCAHSNTVRS
MAILDNENSF LSASKDRTVR LWVGCQWTYK SHRRSVFSVH FLESSRLVAS CDGSVHVWDP
FVGMMVREME CAKSSMVTVL GTLPAPHHGL VTASSDSVLR FIDVRSGSLS HEFRCSTIPA
GQIRCLAVSP DCRWLAVGHS TGVLSTIDVR TGLLIGSWKG HENDVIQVKT VNSKNFVTTS
LDQTVNLWGK EDSKPIQSHK GFSDSVNCIN LFEDSVICAY AQNRIGVRSF KGKPAGASSK
LKPDVFKGVL TSMEVLPLNR LLLLGADSGN ITLLA
//
