ID R7UCL8_CAPTE Unreviewed; 389 AA.
AC R7UCL8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=inositol-polyphosphate 5-phosphatase {ECO:0000256|ARBA:ARBA00012997};
DE EC=3.1.3.56 {ECO:0000256|ARBA:ARBA00012997};
GN ORFNames=CAPTEDRAFT_131585 {ECO:0000313|EMBL:ELU03856.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU03856.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU03856.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU03856.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP131585}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC type I family. {ECO:0000256|ARBA:ARBA00023599}.
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DR EMBL; AMQN01008323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB302824; ELU03856.1; -; Genomic_DNA.
DR AlphaFoldDB; R7UCL8; -.
DR STRING; 283909.R7UCL8; -.
DR EnsemblMetazoa; CapteT131585; CapteP131585; CapteG131585.
DR HOGENOM; CLU_057709_1_0_1; -.
DR OMA; GDHKPVM; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR039737; INPP5A.
DR InterPro; IPR000300; IPPc.
DR PANTHER; PTHR12997:SF2; INOSITOL POLYPHOSPHATE-5-PHOSPHATASE A; 1.
DR PANTHER; PTHR12997; TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 6..384
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
SQ SEQUENCE 389 AA; 45042 MW; BDAA41693460FA0F CRC64;
MATQRPYTKV LLVTANVGSI FEDPEKMLKM WLAEFLATVK RLEPDFLAVH CQEVGGKNYE
ESMQHVNQFI KTLLASDGMQ SFDKARIFLD EDFTAVDKFT ALGNLYFIRD TVTNIHIWDY
EGLEFVPVVG KEVLSGNIEG VTIKEKAKFP QEFFPDFKWS RKGFIRTRWN ICNTIFDLIN
IHLFHDASNI IAMETSPSVY SENRRRTLIH TLKRFETDDY TKHPFFLFGD FNFRLDTHDL
IKKLTDKAIA QQTLGKKNEV SKIMYTANDN GKVVLTIGKK DFDHMNHNNV FSNNNGQWLL
KYDREPSAYK DCLSEHEIMF PPSYPFSEDV SEGASYMKTR CPAYCDRIMF TDSTKDLLYD
DGQTPEYNMI GSNVCMGDHK VHVNLMCLC
//
