ID R7UFY7_CAPTE Unreviewed; 818 AA.
AC R7UFY7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Pyruvate carboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_225810 {ECO:0000313|EMBL:ELU02202.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU02202.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU02202.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU02202.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP225810}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01025141; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQN01025142; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQN01025143; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB304248; ELU02202.1; -; Genomic_DNA.
DR AlphaFoldDB; R7UFY7; -.
DR STRING; 283909.R7UFY7; -.
DR EnsemblMetazoa; CapteT225810; CapteP225810; CapteG225810.
DR HOGENOM; CLU_000395_4_0_1; -.
DR OMA; HCTSGMA; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004736; F:pyruvate carboxylase activity; IEA:InterPro.
DR GO; GO:0006094; P:gluconeogenesis; IEA:InterPro.
DR GO; GO:0006090; P:pyruvate metabolic process; IEA:InterPro.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.10.600.10; pyruvate carboxylase f1077a mutant domain; 2.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR005930; Pyruv_COase.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR PANTHER; PTHR43778; PYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR43778:SF2; PYRUVATE CARBOXYLASE, MITOCHONDRIAL; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 1..109
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 203..472
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 818 AA; 91027 MW; 7A89C83A9BC5DFFE CRC64;
MTCEDPTKNF QPDTGKITVF RTAEGMGIRL DSASAYPGAV ISPYYDSLLV KLIAHANNHE
RACAKMLRAL REFRVKGIKT NEPFLVNVLR HPKFLAGVLD TNFIDENKRL FKFEKAENRA
QKLLYYMADV VVNGPSTPLI TKIPPAKIIP TVPHVHAHQA VGRQGVHYMY KPTEVAKLSG
WRDILTEQGP EAFAKAIRAH KGLLLTDTTM RDAHQSLLST RIRTYDLKRI APFVAQELDG
LLSLENWGGA TFDVCLRFLH ECPWERLETL RELCPNIPFQ MLLRGANAVG YTTYPDNVVY
KFCEQAVKSG MDIFRIFDSL NYIPNMVIGM NAVRKAGGVV EATVAYSGDV SDPSMTKYDL
TYYMDLVDQL VAAGTHILGI KDMAGVLKPQ AARILIGSVR QKYPDLPIHV HCHDTAGTGV
ASMLAAAEAG ADIVDCAVDS MSGMTSQPSM GAIISSLERT PLDTGLSLAP VAKYSAYWEQ
ARQLYGPFEC TATLKSGNSD IFMSQIPGGQ YTNMHFQACS LGLSDQFEEV KRMYSVADNL
LGGLIKVTPS SKVVGDLAQF MVQNKLSAKD VQEKAAELSF PHSVIKFMQG YIGQPYGGFP
EPLRTKEFEG RPGEDMPPLD FAKLKEELTT QWGDIITDQD TLSAALYPDV FRDYKEFRRE
FGPVDKLDTR TFLVGPDIAD EIEIQIEKGK ILHIKLLAQG HVTSQGNREV FFELHGQLSS
VAVKDKEALK RSVSDPVVVK INAFSHDTGM PALVLIQSRS VVSEKYRVKK KDLNFGAKLQ
TIEVWKTKVM SIFATFTKAW ERMCITMYYI SVFSDILT
//
