ID   R7UKP0_CAPTE            Unreviewed;      1107 AA.
AC   R7UKP0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   RecName: Full=HEAT repeat-containing protein 6 {ECO:0000256|ARBA:ARBA00015263};
GN   ORFNames=CAPTEDRAFT_228236 {ECO:0000313|EMBL:ELU07074.1};
OS   Capitella teleta (Polychaete worm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC   Sedentaria; Scolecida; Capitellidae; Capitella.
OX   NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU07074.1};
RN   [1] {ECO:0000313|Proteomes:UP000014760}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA   Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA   Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA   Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA   Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA   Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ELU07074.1, ECO:0000313|Proteomes:UP000014760}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU07074.1,
RC   ECO:0000313|Proteomes:UP000014760};
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
RN   [3] {ECO:0000313|EnsemblMetazoa:CapteP228236}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; AMQN01007193; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KB300180; ELU07074.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7UKP0; -.
DR   STRING; 283909.R7UKP0; -.
DR   EnsemblMetazoa; CapteT228236; CapteP228236; CapteG228236.
DR   HOGENOM; CLU_007141_1_0_1; -.
DR   OMA; VRTNAAW; -.
DR   Proteomes; UP000014760; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR025283; DUF4042.
DR   PANTHER; PTHR13366:SF0; HEAT REPEAT-CONTAINING PROTEIN 6; 1.
DR   PANTHER; PTHR13366; MALARIA ANTIGEN-RELATED; 1.
DR   Pfam; PF13251; DUF4042; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT   DOMAIN          353..533
FT                   /note="DUF4042"
FT                   /evidence="ECO:0000259|Pfam:PF13251"
FT   REGION          271..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          650..671
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..286
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1107 AA;  122518 MW;  BF2CFF69ACC78F86 CRC64;
     MEHELCFDQN PFAAGEVRKF RELRLKLLKL VYKDNEEYLA ELTELLDALN SLEYSHKFVR
     EETVGELLAQ CCYLVPLANE RLVSKFCLLI CNLVNKQQLV LVERLETVTE YVVRGLHKCT
     TWVVFDLLRA LGVIVYENTG RLTQYHEDLL GEHGLLIRLC TSQDENVLRA VIQCIENLTI
     REDCQVRCFR CLLSLLQTPK PTAMETMTHC KLLMCGLKGM QNLLVVTHCL PADALGPLLA
     VLKVLMFHGL PGCPTNIPLS LYPTPLTQFD PSTSSSAATT VTPKKASNVK KGKKKQAQRK
     KKGGGEEEGE EEEKPNTEDV YAMSWSKVSS SDSEYSDAEG GVQASRTKNT YSRVRQCAFC
     SFHALIKATE RRVMFGYWTC FIPDSPGEAA MAHTLLAAIL KDPSTKSRRA AIAVLTVLLE
     SSRQFLMAAE DSDQYRSAPY TPFSVTLGHM IKEIHTCLLQ ALSSEASLLA ITQIIKCLAT
     LILNVPYQRL QAGLLTAVVT QIPAFISHRD PNICVACLTC LGSVASSQAQ PTEVNALLLP
     PRLTEAPPSE QATASGELSW VLKICVKNTA PSLLLDPAER SSSKTAAVQP LPVRLESLQL
     LSQLAKSHFG VLRPRLTLIR DLIQLCFMDK DPAVQLHGAK LLDGVSTVVQ QQQQQQQEEG
     EGEAPPALPR EPMSKQQMLD LWSPLLAGPV PNLLQTATYE AVKYTLCDCL ANVGPSVFAL
     LPREQHILCL TLLLGLASDE DFHVRAAAVR ALGVYVRYPC LREDVCFMAD AANAVLTALD
     EQSLVVRAKA AWALGNLSNA IVLNRSHEAF VHGFSDMLLL KLFEVATAAS KDSDRVRSNA
     VRALGNLLRY LPPKSHGEVG LQSEALMFMF AATDSCRFKQ TVEAAIESLI TNVATGTMKV
     RWNSCYALGN MLQNEPLLLD SQAADSARMR SKVFRTLAEA VHDCRNFKVR INAALALAVP
     SRRSHYGSDF VLIWQSLLRA LQVLEENSDF TEFRYLNSLI EQIGGSLVHL AAILEADDLS
     ALAKDSQHQA LLLCYLEKYK QLIHENHSVS GAQRRTALSE AERNVRSLQP HREEVFLDAL
     SVAFDDCIPD AVELKNPQKS AFVQSYD
//