ID R7ULJ4_CAPTE Unreviewed; 651 AA.
AC R7ULJ4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 13-SEP-2023, entry version 43.
DE RecName: Full=peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
DE EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};
GN ORFNames=CAPTEDRAFT_199088 {ECO:0000313|EMBL:ELU07414.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU07414.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU07414.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU07414.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP199088}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8; Evidence={ECO:0000256|PROSITE-
CC ProRule:PRU00277};
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DR EMBL; AMQN01007095; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB299944; ELU07414.1; -; Genomic_DNA.
DR AlphaFoldDB; R7ULJ4; -.
DR STRING; 283909.R7ULJ4; -.
DR EnsemblMetazoa; CapteT199088; CapteP199088; CapteG199088.
DR HOGENOM; CLU_007194_0_0_1; -.
DR OMA; RMGMSKI; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.40; -; 1.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR PANTHER; PTHR44927; FK506-BINDING PROTEIN 15; 1.
DR PANTHER; PTHR44927:SF1; FK506-BINDING PROTEIN 15; 1.
DR Pfam; PF00254; FKBP_C; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR PROSITE; PS50059; FKBP_PPIASE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00277}.
FT DOMAIN 119..210
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT REGION 25..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 495..543
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 246..267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 70915 MW; 238AE5089B10F817 CRC64;
MFSFGGEEDG DEFLLPSGGN SKLASLFGAD ASGSPSSNES LKYTAPKEPK KVQTAAPSAS
GLLIDGKYSS QGKLGAAVIG THSPPDIALA KANATEGAMD AVVSQDLFLP PEGSPLELGD
SVEVRFTGWL FNEGTAGEVF ETNTSSEKLL RCKLGKGKII KGHEEGLLGM KKGGKRLLVI
PPQLGYGSDG KQGIPSNATL VIESEIVRVG VNLLKFIVIT GLFNLKVKHM KDKGKSTPQS
SRSTTPVPKE EEEEDEADGR KSRTKSITES ISDQLTTVCI HGLSTDVLYV ISHFQQPNKS
DKAKLISRMA KMGQPMLPRG SIGHDDHEVP TTPGSVEGKP DIPIKPATIN QTHEGVAYSQ
PPSAAAQPVV GGYPPQYIQP MAAQQPPLAP PTVMQGIPNG NQMALYQSSM QQPGYPPAPY
NAIYGQQPYQ AAPPPAPPST DTPVLLSETR QQNTEVRLCL SKVSDKVDRI MEKVDHMHSQ
QQQIAQPNTS YNMETSALMH NIQRIVQENE RLKKEVFEKS SRIESQNDKI SDLLHRNQKF
MEQSNVLLEQ RNDSFKSTAT QSQARVLTLE QEKVELSSRL SAVTSEVGVL QLELTAVKKV
AAESQLQLQK SLGEEEKYRE QINKDKLTSS ENCFLFVRLS LIRARELLEI L
//
